Delivery of fluorescent nanoparticles to the brain

Olga Shimoni*, Bingyang Shi, Paul A. Adlard, Ashley I. Bush

*Corresponding author for this work

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Nanotechnology applications in neuroscience promises to deliver significant scientific and technological breakthroughs, providing answers to unresolved questions regarding the processes occurring in the brain. In this perspective, we provide a short background on two distinct fluorescent nanoparticles and summarize several studies focussed on achieving delivery of these into the brain and their interaction with brain tissue. Furthermore, we discuss challenges and opportunities for further development of nanoparticle-based therapies for targeting delivery of drugs across the blood-brain barrier.

Original languageEnglish
Pages (from-to)405-409
Number of pages5
JournalJournal of Molecular Neuroscience
Volume60
Issue number3
DOIs
Publication statusPublished - 1 Nov 2016

Keywords

  • blood-brain barrier
  • fluorescent nanoparticles
  • multifunctional nanoparticles
  • nanodiamonds
  • upconversion nanoparticles

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