Delivery of fluorescent nanoparticles to the brain

Olga Shimoni; Bingyang Shi; Paul A. Adlard; Ashley I. Bush

doi:10.1007/s12031-016-0833-5

Delivery of fluorescent nanoparticles to the brain

Olga Shimoni^*, Bingyang Shi, Paul A. Adlard, Ashley I. Bush

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Nanotechnology applications in neuroscience promises to deliver significant scientific and technological breakthroughs, providing answers to unresolved questions regarding the processes occurring in the brain. In this perspective, we provide a short background on two distinct fluorescent nanoparticles and summarize several studies focussed on achieving delivery of these into the brain and their interaction with brain tissue. Furthermore, we discuss challenges and opportunities for further development of nanoparticle-based therapies for targeting delivery of drugs across the blood-brain barrier.

Original language	English
Pages (from-to)	405-409
Number of pages	5
Journal	Journal of Molecular Neuroscience
Volume	60
Issue number	3
DOIs	https://doi.org/10.1007/s12031-016-0833-5
Publication status	Published - 1 Nov 2016

Keywords

blood-brain barrier
fluorescent nanoparticles
multifunctional nanoparticles
nanodiamonds
upconversion nanoparticles

Access to Document

10.1007/s12031-016-0833-5

Cite this

@article{6581f6bd731843848df1a85f6d56af62,

title = "Delivery of fluorescent nanoparticles to the brain",

abstract = "Nanotechnology applications in neuroscience promises to deliver significant scientific and technological breakthroughs, providing answers to unresolved questions regarding the processes occurring in the brain. In this perspective, we provide a short background on two distinct fluorescent nanoparticles and summarize several studies focussed on achieving delivery of these into the brain and their interaction with brain tissue. Furthermore, we discuss challenges and opportunities for further development of nanoparticle-based therapies for targeting delivery of drugs across the blood-brain barrier.",

keywords = "blood-brain barrier, fluorescent nanoparticles, multifunctional nanoparticles, nanodiamonds, upconversion nanoparticles",

author = "Olga Shimoni and Bingyang Shi and Adlard, {Paul A.} and Bush, {Ashley I.}",

year = "2016",

month = nov,

day = "1",

doi = "10.1007/s12031-016-0833-5",

language = "English",

volume = "60",

pages = "405--409",

journal = "Journal of Molecular Neuroscience",

issn = "0895-8696",

publisher = "Springer, Springer Nature",

number = "3",

}

TY - JOUR

T1 - Delivery of fluorescent nanoparticles to the brain

AU - Shimoni, Olga

AU - Shi, Bingyang

AU - Adlard, Paul A.

AU - Bush, Ashley I.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Nanotechnology applications in neuroscience promises to deliver significant scientific and technological breakthroughs, providing answers to unresolved questions regarding the processes occurring in the brain. In this perspective, we provide a short background on two distinct fluorescent nanoparticles and summarize several studies focussed on achieving delivery of these into the brain and their interaction with brain tissue. Furthermore, we discuss challenges and opportunities for further development of nanoparticle-based therapies for targeting delivery of drugs across the blood-brain barrier.

AB - Nanotechnology applications in neuroscience promises to deliver significant scientific and technological breakthroughs, providing answers to unresolved questions regarding the processes occurring in the brain. In this perspective, we provide a short background on two distinct fluorescent nanoparticles and summarize several studies focussed on achieving delivery of these into the brain and their interaction with brain tissue. Furthermore, we discuss challenges and opportunities for further development of nanoparticle-based therapies for targeting delivery of drugs across the blood-brain barrier.

KW - blood-brain barrier

KW - fluorescent nanoparticles

KW - multifunctional nanoparticles

KW - nanodiamonds

KW - upconversion nanoparticles

UR - http://www.scopus.com/inward/record.url?scp=84988688661&partnerID=8YFLogxK

U2 - 10.1007/s12031-016-0833-5

DO - 10.1007/s12031-016-0833-5

M3 - Article

C2 - 27660216

AN - SCOPUS:84988688661

SN - 0895-8696

VL - 60

SP - 405

EP - 409

JO - Journal of Molecular Neuroscience

JF - Journal of Molecular Neuroscience

IS - 3

ER -

Delivery of fluorescent nanoparticles to the brain

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this