Describing patterns of care in pancreatic cancer a population-based study: a population-based study

Elizabeth A. Burmeister, Dianne L OʼConnell, Vanessa L. Beesley, David Goldstein, Helen M. Gooden, Monika Janda, Susan J. Jordan, Neil D. Merrett, Madeleine E Payne, David Keith Wyld, Rachel E. Neale, Pancreatic Cancer Patterns of Care Study Group, Howard Gurney

Research output: Contribution to journalArticleResearchpeer-review

Abstract

OBJECTIVES: Despite pancreatic cancer being the fifth highest cause of cancer death in developed regions, there is a paucity of population-based management details for patients with pancreatic cancer. The objective of this study was to reflect on current practice and outcomes to facilitate future improvement.

METHODS: A comprehensive population-based patterns-of-care study in 2 Australian states was conducted. Patients diagnosed with pancreatic adenocarcinoma between July 2009 and June 2011 were identified by cancer registries, and detailed clinical data were collected from medical records.

RESULTS: Data were collected for 1863 patients, 96% of those eligible. The majority resided in major cities; their median age was 72 years, and 54% were men. Over half of the cases (58%) had metastatic disease at diagnosis. Resection was attempted for 20% of patients but only completed in 15%. The uptake of adjuvant chemotherapy (76%) and the proportion alive at 1-year (22%) were higher than reported in previous population-based reports. Of those with no complete surgical resection, 43% received palliative chemotherapy.

CONCLUSIONS: This population-based overview of the management of patients with pancreatic cancer suggests that, despite evidence that the proportion surviving and the use of adjuvant chemotherapy has increased, there may still be underutilization of cancer-directed therapies.

LanguageEnglish
Pages1259-65
Number of pages7
JournalPancreas
Volume44
Issue number8
DOIs
Publication statusPublished - Nov 2015
Externally publishedYes

Fingerprint

Pancreatic Neoplasms
Population
Adjuvant Chemotherapy
Neoplasms
Medical Records
Registries
Cause of Death
Adenocarcinoma
Drug Therapy
Therapeutics

Keywords

  • pancreatic cancer
  • population-based
  • patterns of care
  • surgery
  • chemotherapy
  • health services

Cite this

Burmeister, E. A., OʼConnell, D. L., Beesley, V. L., Goldstein, D., Gooden, H. M., Janda, M., ... Pancreatic Cancer Patterns of Care Study Group (2015). Describing patterns of care in pancreatic cancer a population-based study: a population-based study. Pancreas, 44(8), 1259-65. https://doi.org/10.1097/MPA.0000000000000384
Burmeister, Elizabeth A. ; OʼConnell, Dianne L ; Beesley, Vanessa L. ; Goldstein, David ; Gooden, Helen M. ; Janda, Monika ; Jordan, Susan J. ; Merrett, Neil D. ; Payne, Madeleine E ; Wyld, David Keith ; Neale, Rachel E. ; Pancreatic Cancer Patterns of Care Study Group. / Describing patterns of care in pancreatic cancer a population-based study : a population-based study. In: Pancreas. 2015 ; Vol. 44, No. 8. pp. 1259-65.
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Burmeister, EA, OʼConnell, DL, Beesley, VL, Goldstein, D, Gooden, HM, Janda, M, Jordan, SJ, Merrett, ND, Payne, ME, Wyld, DK, Neale, RE & Pancreatic Cancer Patterns of Care Study Group 2015, 'Describing patterns of care in pancreatic cancer a population-based study: a population-based study', Pancreas, vol. 44, no. 8, pp. 1259-65. https://doi.org/10.1097/MPA.0000000000000384

Describing patterns of care in pancreatic cancer a population-based study : a population-based study. / Burmeister, Elizabeth A.; OʼConnell, Dianne L; Beesley, Vanessa L.; Goldstein, David; Gooden, Helen M.; Janda, Monika; Jordan, Susan J.; Merrett, Neil D.; Payne, Madeleine E; Wyld, David Keith; Neale, Rachel E.; Pancreatic Cancer Patterns of Care Study Group.

In: Pancreas, Vol. 44, No. 8, 11.2015, p. 1259-65.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Describing patterns of care in pancreatic cancer a population-based study

T2 - Pancreas

AU - Burmeister, Elizabeth A.

AU - OʼConnell, Dianne L

AU - Beesley, Vanessa L.

AU - Goldstein, David

AU - Gooden, Helen M.

AU - Janda, Monika

AU - Jordan, Susan J.

AU - Merrett, Neil D.

AU - Payne, Madeleine E

AU - Wyld, David Keith

AU - Neale, Rachel E.

AU - Pancreatic Cancer Patterns of Care Study Group

AU - Gurney, Howard

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N2 - OBJECTIVES: Despite pancreatic cancer being the fifth highest cause of cancer death in developed regions, there is a paucity of population-based management details for patients with pancreatic cancer. The objective of this study was to reflect on current practice and outcomes to facilitate future improvement.METHODS: A comprehensive population-based patterns-of-care study in 2 Australian states was conducted. Patients diagnosed with pancreatic adenocarcinoma between July 2009 and June 2011 were identified by cancer registries, and detailed clinical data were collected from medical records.RESULTS: Data were collected for 1863 patients, 96% of those eligible. The majority resided in major cities; their median age was 72 years, and 54% were men. Over half of the cases (58%) had metastatic disease at diagnosis. Resection was attempted for 20% of patients but only completed in 15%. The uptake of adjuvant chemotherapy (76%) and the proportion alive at 1-year (22%) were higher than reported in previous population-based reports. Of those with no complete surgical resection, 43% received palliative chemotherapy.CONCLUSIONS: This population-based overview of the management of patients with pancreatic cancer suggests that, despite evidence that the proportion surviving and the use of adjuvant chemotherapy has increased, there may still be underutilization of cancer-directed therapies.

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Burmeister EA, OʼConnell DL, Beesley VL, Goldstein D, Gooden HM, Janda M et al. Describing patterns of care in pancreatic cancer a population-based study: a population-based study. Pancreas. 2015 Nov;44(8):1259-65. https://doi.org/10.1097/MPA.0000000000000384