@inproceedings{62d5d57ae94d4c46a1f5dd35a4f4fd7e,
title = "Design of high power LED-based UVA emission system and a photosensitive substance for clinical application in corneal radiation",
abstract = "This work presents an innovative cross-linking procedure to keratoconus treatment, a corneal disease. It includes the development of an ultraviolet controlled emission portable device based on LED source and a new formulation of a photosensitive drug called riboflavin. Thus new formulation improves drug administration by its transepithelial property. The UV reaction with riboflavin in corneal tissue leads to a modification of corneal collagen fibers, turning them more rigid and dense, and consequently restraining the advance of the disease. We present the control procedures to maintain UV output power stable up to 45mw/cm2, the optical architecture that leads to a homogeneous UV spot and the new formulation of Riboflavin.",
keywords = "Ultraviolet LED, Cross-linking, Keratoconus, Riboflavin, Transepithelial, PID control system for LEDs, Close loop system for LED, UV based Optical system",
author = "Mota, {Alessandro D.} and Cestari, {Andr{\'e} M.} and {De Oliveira}, {Andr{\'e} O.} and Oliveira, {Anselmo G.} and Terruggi, {Cristina H. B.} and Giuliano Rossi and Castro, {Jarbas C.} and Ligab{\^o}, {Jo{\~a}o P. B.} and Ortega, {Tiago A.} and Tiago Rosa",
year = "2015",
doi = "10.1117/12.2187265",
language = "English",
series = "Proceedings of SPIE",
publisher = "SPIE",
pages = "95710X--1--95710X--13",
editor = "Kane, {Matthew H.} and Jianzhong Jiao and Nikolaus Dietz and Jian-Jang Huang",
booktitle = "Fourteenth International Conference on Solid State Lighting and LED-Based Illumination Systems",
address = "United States",
note = "14th International Conference on Solid State Lighting and LED-Based Illumination Systems ; Conference date: 12-08-2015 Through 13-08-2015",
}