Deterministic lateral displacement occurs without contact at inertial flow rates

William J. Monck, Calum P. Mallorie, Rohan R. Vernekar, Timm Krüger, David W. Inglis*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

The movement of microparticles through microfluidic systems is relevant to a wide range of technologies. Modelling the flow field in the absence of particles is routine. However, predicting the path of particles is challenging as it results from non-steady-state interactions between the fluid boundaries, the pressure gradient and the particle. Lattice Boltzman method (LBM) is able to accurately solve this dynamic problem, and is here applied to Deterministic Lateral Displacement (DLD) microfluidics. We show that inertia causes i) separation without post-pillar contact and ii) reduced critical particle size. We also show that simulations in 2D exaggerate the magnitude of this reduction.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages649-650
Number of pages2
ISBN (Electronic)9781733419017
Publication statusAccepted/In press - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: 4 Oct 20209 Oct 2020

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period4/10/209/10/20

Keywords

  • Deterministic lateral displacement
  • High throughput
  • Inertial microfluidics
  • Modelling
  • Simulation

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