Developing decision support systems in clinical bioinformatics

Vitali Sintchenko*, Enrico Coiera

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


There is a growing demand for tools to support clinicians utilize genomic results generated by molecular diagnostic and cytogenetic methods in support of their decision-making. This chapter reviews existing experience and methods for the design, implementation and evaluation of clinical bioinformatics electronic decision support systems (EDSS). It provides a roadmap for identifying decision tasks for automation and selecting optimal tools for building task-specific systems. Key success factors for EDSS implementation and evaluation are also outlined.

Original languageEnglish
Pages (from-to)331-351
Number of pages21
JournalMethods in molecular medicine
Publication statusPublished - 2008
Externally publishedYes


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