Development of a low cost microP-based blood gas monitor.

H. Nazeran*, J. D. Macrow, P. Pilowski

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)


    A low cost microprocessor-based system for continuous in-vivo measurement of blood pH and pCO2 using a biosensor is being developed. The biosensor is a pH Ti2O3 ISFET (Ion Sensitive Field Effect Transistor) with a sensitivity of -56 mV/pH and a linear response over physiologically meaningful blood pH range of 6.5 to 8.0. The ISFET chip is bonded onto a printed circuit board substrate to enable reliable and robust connections to three wires. The small sensor tip sized of 0.95 mm facilitates its incorporation into a catheter tip and its placement into a rat's artery. A microcontroller supervises preusage calibration, data logging, display of alphanumeric information on a LCD (liquid crystal display) unit, and resettable visual & audio alarm indicators. Preliminary clinical testing are underway to perfect the system and use it on a routine basis to monitor the physiological state of laboratory animals during neurophysiological experiments.

    Original languageEnglish
    Pages (from-to)143-145
    Number of pages3
    JournalAustralasian Physical and Engineering Sciences in Medicine
    Issue number3
    Publication statusPublished - Sept 1995


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