Development of a new dyspepsia impact scale: the nepean dyspepsia index

N J Talley; M Haque; J W Wyeth; N H Stace; G N Tytgat; Vincenzo Stanghellini; G. Holtmann; Marleen Verlinden; Mike Jones

doi:10.1046/j.1365-2036.1999.00445.x

Development of a new dyspepsia impact scale: the nepean dyspepsia index

N J Talley, M Haque, J W Wyeth, N H Stace, G N Tytgat, Vincenzo Stanghellini, G. Holtmann, Marleen Verlinden, Mike Jones

Research output: Contribution to journal › Article › peer-review

193 Citations (Scopus)

Abstract

BACKGROUND: There is not at present a suitable disease-specific health-related quality of life instrument for uninvestigated dyspepsia and functional (non-ulcer) dyspepsia.

AIM: To develop a new multi-dimensional disease-specific instrument.

METHODS: The Nepean Dyspepsia Index (NDI) was designed to measure impairment of a subject's ability to engage in relevant aspects of their life and also their enjoyment of these aspects; in addition, the individual importance of each aspect is assessed. A 42-item quality of life measure was developed and tested, both in out-patients presenting to general practice with upper gastrointestinal complaints (n = 113) and in a randomly chosen population-based sample (n = 347).

RESULTS: Adequate face and content validity was documented by an expert panel. Factor analysis identified four clinically relevant subscales: interference with activities of daily living, work, enjoyment of life and emotional well-being; lack of knowledge and control over the illness; disturbance to eating or drinking; and disturbance to sleep because of dyspepsia. These scales had high internal consistency. Both symptoms and the quality of life scores discriminated dyspepsia from health.

CONCLUSION: The Nepean Dyspepsia Index is a reliable and valid disease-specific index for dyspepsia, measuring symptoms and health-related quality of life.

Original language	English
Pages (from-to)	225-235
Number of pages	11
Journal	Alimentary Pharmacology and Therapeutics
Volume	13
Issue number	2
DOIs	https://doi.org/10.1046/j.1365-2036.1999.00445.x
Publication status	Published - Feb 1999
Externally published	Yes

Keywords

Adult
Aged
Dyspepsia
Female
Humans
Male
Middle Aged
Quality of Life
Journal Article
Research Support, Non-U.S. Gov't

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10.1046/j.1365-2036.1999.00445.x

Cite this

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title = "Development of a new dyspepsia impact scale: the nepean dyspepsia index",

abstract = "BACKGROUND: There is not at present a suitable disease-specific health-related quality of life instrument for uninvestigated dyspepsia and functional (non-ulcer) dyspepsia.AIM: To develop a new multi-dimensional disease-specific instrument.METHODS: The Nepean Dyspepsia Index (NDI) was designed to measure impairment of a subject's ability to engage in relevant aspects of their life and also their enjoyment of these aspects; in addition, the individual importance of each aspect is assessed. A 42-item quality of life measure was developed and tested, both in out-patients presenting to general practice with upper gastrointestinal complaints (n = 113) and in a randomly chosen population-based sample (n = 347).RESULTS: Adequate face and content validity was documented by an expert panel. Factor analysis identified four clinically relevant subscales: interference with activities of daily living, work, enjoyment of life and emotional well-being; lack of knowledge and control over the illness; disturbance to eating or drinking; and disturbance to sleep because of dyspepsia. These scales had high internal consistency. Both symptoms and the quality of life scores discriminated dyspepsia from health.CONCLUSION: The Nepean Dyspepsia Index is a reliable and valid disease-specific index for dyspepsia, measuring symptoms and health-related quality of life.",

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AU - Talley, N J

AU - Haque, M

AU - Wyeth, J W

AU - Stace, N H

AU - Tytgat, G N

AU - Stanghellini, Vincenzo

AU - Holtmann, G.

AU - Verlinden, Marleen

AU - Jones, Mike

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KW - Aged

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Development of a new dyspepsia impact scale: the nepean dyspepsia index

Abstract

Keywords

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