Development of a Point-of-Care diagnostic smart sensing system to detect creatinine levels

Sumedha Prabhu, Chinthaka Gooneratne, Ky Anh Hoang, Subhas Mukhopadhyay

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

In this work, a non-invasive Electrochemical Impedance Spectroscopy (EIS) Point-of-Care (PoC) diagnostic device to detect the creatinine concentration from the serum is presented. A Micro-Electro-Mechanical Systems (MEMS) sensor was used for measuring the electrochemical properties of Sample Under Test (SUT). The EIS technique was utilised along with the sensor to find out different creatinine concentrations in heat-inactivated serum samples. Creatinine specific Molecularly Imprinted Polymerization (MIP)-coated sensor was used to measure the levels of creatinine followed by the development of a LoRaWAN-based PoC diagnostic device. In the next step, the results obtained from the diagnostic device were cross-verified by using standard Creatinine Colorimetric Assay Kit. The results were found to be promising to further continue the research.

Original languageEnglish
Title of host publication2020 IEEE 63rd International Midwest Symposium on Circuits and Systems (MWSCAS)
Subtitle of host publicationon-line proceedings
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages77-80
Number of pages4
ISBN (Electronic)9781728180588, 9781538629161
ISBN (Print)9781728180595
DOIs
Publication statusPublished - 2020
Event63rd IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2020 - Springfield, United States
Duration: 9 Aug 202012 Aug 2020

Publication series

Name
ISSN (Print)1548-3746
ISSN (Electronic)1558-3899

Conference

Conference63rd IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2020
CountryUnited States
CitySpringfield
Period9/08/2012/08/20

Keywords

  • Electrochemical Impedance Spectroscopy (EIS)
  • Point-of-Care (PoC)
  • Micro-Electro-Mechanical Systems (MEMS)
  • Molecularly Imprinted Polymerization (MIP)
  • Colorimetric Assay

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