Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen

Nasrin Afsarimanesh; M. E E Alahi; Subhas Mukhopadhyay; Marlena Kruger; Pak Lam Yu

doi:10.1109/ICSensT.2016.7796240

Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen

Nasrin Afsarimanesh^*, M. E E Alahi, Subhas Mukhopadhyay, Marlena Kruger, Pak Lam Yu

^*Corresponding author for this work

Faculty of Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

4 Citations (Scopus)

Abstract

This paper presents a label-free and non-invasive technique for selective detection of C-terminal telopeptide type I collagen (CTx-I) by employing Electrochemical Impedance Spectroscopy to measure sample impedance. Molecular imprinted polymer, containing artificial recognition sites for CTx-was prepared by precipitation polymerization using CTx-I peptide as a template, methacrylic acid as a functional monomer and ethylene glycol methacrylate as the cross-linker. A high penetration depth planar interdigital sensor was functionalized by a self-assembled monolayer along with the synthesized MIP. Different concentrations of CTx-I sample solutions were tested using the proposed sensing system. High-Performance Liquid chromatography diode array system was used to validate the results.

Original language	English
Title of host publication	2016 10th International Conference on Sensing Technology, ICST 2016
Place of Publication	Piscataway, NJ
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Pages	1-5
Number of pages	5
ISBN (Electronic)	9781509007967
DOIs	https://doi.org/10.1109/ICSensT.2016.7796240
Publication status	Published - 22 Dec 2016
Event	10th International Conference on Sensing Technology, ICST 2016 - Nanjing, China Duration: 11 Nov 2016 → 13 Nov 2016

Other

Other	10th International Conference on Sensing Technology, ICST 2016
Country/Territory	China
City	Nanjing
Period	11/11/16 → 13/11/16

Keywords

bone turnover markers
electrochemical impedance spectroscopy
interdigital sensor
molecular imprinted polymers

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10.1109/ICSensT.2016.7796240

Cite this

Afsarimanesh, N., Alahi, M. E. E., Mukhopadhyay, S., Kruger, M., & Yu, P. L. (2016). Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen. In 2016 10th International Conference on Sensing Technology, ICST 2016 (pp. 1-5). Article 7796240 Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/ICSensT.2016.7796240

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abstract = "This paper presents a label-free and non-invasive technique for selective detection of C-terminal telopeptide type I collagen (CTx-I) by employing Electrochemical Impedance Spectroscopy to measure sample impedance. Molecular imprinted polymer, containing artificial recognition sites for CTx-was prepared by precipitation polymerization using CTx-I peptide as a template, methacrylic acid as a functional monomer and ethylene glycol methacrylate as the cross-linker. A high penetration depth planar interdigital sensor was functionalized by a self-assembled monolayer along with the synthesized MIP. Different concentrations of CTx-I sample solutions were tested using the proposed sensing system. High-Performance Liquid chromatography diode array system was used to validate the results.",

keywords = "bone turnover markers, electrochemical impedance spectroscopy, interdigital sensor, molecular imprinted polymers",

author = "Nasrin Afsarimanesh and Alahi, {M. E E} and Subhas Mukhopadhyay and Marlena Kruger and Yu, {Pak Lam}",

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Afsarimanesh, N, Alahi, MEE, Mukhopadhyay, S, Kruger, M & Yu, PL 2016, Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen. in 2016 10th International Conference on Sensing Technology, ICST 2016., 7796240, Institute of Electrical and Electronics Engineers (IEEE), Piscataway, NJ, pp. 1-5, 10th International Conference on Sensing Technology, ICST 2016, Nanjing, China, 11/11/16. https://doi.org/10.1109/ICSensT.2016.7796240

Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen. / Afsarimanesh, Nasrin; Alahi, M. E E; Mukhopadhyay, Subhas et al.
2016 10th International Conference on Sensing Technology, ICST 2016. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE), 2016. p. 1-5 7796240.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

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AU - Alahi, M. E E

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AU - Kruger, Marlena

AU - Yu, Pak Lam

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AB - This paper presents a label-free and non-invasive technique for selective detection of C-terminal telopeptide type I collagen (CTx-I) by employing Electrochemical Impedance Spectroscopy to measure sample impedance. Molecular imprinted polymer, containing artificial recognition sites for CTx-was prepared by precipitation polymerization using CTx-I peptide as a template, methacrylic acid as a functional monomer and ethylene glycol methacrylate as the cross-linker. A high penetration depth planar interdigital sensor was functionalized by a self-assembled monolayer along with the synthesized MIP. Different concentrations of CTx-I sample solutions were tested using the proposed sensing system. High-Performance Liquid chromatography diode array system was used to validate the results.

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KW - electrochemical impedance spectroscopy

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Afsarimanesh N, Alahi MEE, Mukhopadhyay S, Kruger M, Yu PL. Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen. In 2016 10th International Conference on Sensing Technology, ICST 2016. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). 2016. p. 1-5. 7796240 doi: 10.1109/ICSensT.2016.7796240

Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagen

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