Development of the immune system and immunological protection in marsupial pouch young

J. M. Old; E. M. Deane

doi:10.1016/S0145-305X(00)00008-2

Development of the immune system and immunological protection in marsupial pouch young

J. M. Old, E. M. Deane^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

93 Citations (Scopus)

Abstract

At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the neonatal marsupial in a microbially rich environment is dependent on maternal strategies, including immunoglobulin transfer via milk and, in some species, prenatally via the yolk sac placenta. It is also likely that pouch secretions play a role. This review summarizes our current knowledge of the pathway of immunological development in marsupials and the protection and threats afforded by the pouch environment. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	445-454
Number of pages	10
Journal	Developmental and Comparative Immunology
Volume	24
Issue number	5
DOIs	https://doi.org/10.1016/S0145-305X(00)00008-2
Publication status	Published - 1 Jul 2000

Keywords

Immunocompetence
Marsupials
Ontogeny

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abstract = "At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the neonatal marsupial in a microbially rich environment is dependent on maternal strategies, including immunoglobulin transfer via milk and, in some species, prenatally via the yolk sac placenta. It is also likely that pouch secretions play a role. This review summarizes our current knowledge of the pathway of immunological development in marsupials and the protection and threats afforded by the pouch environment. (C) 2000 Elsevier Science Ltd.",

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AU - Old, J. M.

AU - Deane, E. M.

PY - 2000/7/1

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N2 - At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the neonatal marsupial in a microbially rich environment is dependent on maternal strategies, including immunoglobulin transfer via milk and, in some species, prenatally via the yolk sac placenta. It is also likely that pouch secretions play a role. This review summarizes our current knowledge of the pathway of immunological development in marsupials and the protection and threats afforded by the pouch environment. (C) 2000 Elsevier Science Ltd.

AB - At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the neonatal marsupial in a microbially rich environment is dependent on maternal strategies, including immunoglobulin transfer via milk and, in some species, prenatally via the yolk sac placenta. It is also likely that pouch secretions play a role. This review summarizes our current knowledge of the pathway of immunological development in marsupials and the protection and threats afforded by the pouch environment. (C) 2000 Elsevier Science Ltd.

KW - Immunocompetence

KW - Marsupials

KW - Ontogeny

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DO - 10.1016/S0145-305X(00)00008-2

M3 - Review article

C2 - 10785270

AN - SCOPUS:0034237118

SN - 0145-305X

VL - 24

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EP - 454

JO - Developmental and Comparative Immunology

JF - Developmental and Comparative Immunology

IS - 5

ER -

Development of the immune system and immunological protection in marsupial pouch young

Abstract

Keywords

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