Abstract
Diabetic ketoacidosis (DKA) is a life-threatening complication of type 1 diabetes (T1D), which without treatment leads to death. Fulminant type 1 diabetes (FT1D) is a subtype characterised by a markedly rapid and almost complete destruction of pancreatic β-cells, with acute onset leading to severe metabolic derangement and commonly ICU admission. We present a case of an 18-year-old male presenting with FT1D with two rare complications of pneumomediastinum and stress-induced cardiomyopathy (SIC) with significant myocardial necrosis. We also discuss the aetiology of the pneumomediastinum; the latest thoughts on SIC: moving beyond the simple description of 'Takotsubo cardiomyopathy'; the role of troponins in critical illness; and genetic predisposition for DKA due to FT1D.
Original language | English |
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Pages (from-to) | 64-70 |
Number of pages | 7 |
Journal | Journal of the Intensive Care Society |
Volume | 16 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2015 |
Externally published | Yes |
Keywords
- fulminant type 1 diabetes
- pneumomediastinum
- stress induced cardiomyopathy
- troponin
- Takotsubo cardiomyopathy