Diagnosis and interventions for central serous chorioretinopathy: Review and update

Godfrey Quin, Gerald Liew, I. Van Ho, Mark Gillies, Samantha Fraser-Bell*

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    75 Citations (Scopus)


    Most acute cases of central serous chorioretinopathy resolve spontaneously with minimal visual impairment. The small percentage of eyes developing chronic or recurrent disease that do warrant treatment is often difficult to control. Emergent investigations and treatments have added to the established options available to manage these cases. Optical coherence tomography has proved valuable for both imaging subtle fundoscopic findings and monitoring disease progression. Fluorescein angiography aids identification of pigment epithelial leaks and targets the use of argon laser treatment if outside the fovea. Fluorescein angiography also assists differentiation from other choroidal pathologies such as choroidal neovascularization and polypoidal choroidal vasculopathy. Where the diagnosis is uncertain, indocyanine green angiography can demonstrate classic midphase hyperpermeability. This is also useful to guide the application of photodynamic therapy. Newer treatments such as intravitreal anti-vascular endothelial growth factor are as yet unproven.

    Original languageEnglish
    Pages (from-to)187-200
    Number of pages14
    JournalClinical and Experimental Ophthalmology
    Issue number2
    Publication statusPublished - Mar 2013


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