Diagnosis and monitoring of neurodegenerative diseases

Dominic Rowe; Ewa Goldys; Martin Gosnell; Ayad Anwer

Diagnosis and monitoring of neurodegenerative diseases

Dominic Rowe (Inventor), Ewa Goldys (Inventor), Martin Gosnell (Inventor), Ayad Anwer (Inventor)

Research output: Patent

Abstract

Disclosed is a method for diagnosing a neurodegenerative disease in a subject. The method comprises obtaining from the subject a sample comprising at least one live blood cell, and optionally isolating at least one live blood cell from the sample. The method further comprises generating one or more multispectral or hyperspectral images of the at least one cell, and analysing spectral characteristics of autofluorescence from the at least one cell. Also disclosed is a system configured to aid in the detection or diagnosis of a neurodegenerative disease. Also disclosed is a method for selecting a subject for treatment for a neurodegenerative disease. Also disclosed is a method for monitoring the response of a subject to a therapeutic treatment for a neurodegenerative disease. Also disclosed is a protocol for monitoring the efficacy of a therapeutic treatment for a neurodegenerative disease.

Original language	English
Patent number	WO2020257861
IPC	G01N 21/ 64 A I,G01J 3/28 2006.1,A61B 5/00 2006.1
Priority date	27/06/19
Filing date	26/06/20
Publication status	Published - 30 Dec 2020

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3 Patent

Diagnosis and monitoring of neurodegenerative diseases
Rowe, D., Goldys, E., Gosnell, M. & Anwer, A., 4 May 2022, IPC No. G01N 21/ 64 A I, A61B 5/00, G01J 3/28, Patent No. EP3989806, Priority date 27 Jun 2019, Priority No. AU2019902257
Research output: Patent

Open Access
Diagnosis and monitoring of neurodegenerative diseases
Rowe, D., Goldys, E., Gosnell, M. & Anwer, A., 3 Nov 2022, IPC No. G06T 7/ 00 A I, A61B 5/00, Patent No. US2022351371, Priority date 27 Jun 2019, Priority No. Au2019902257
Research output: Patent

Open Access
Diagnosis and monitoring of neurodegenerative diseases
Rowe, D., Goldys, E., Gosnell, M. & Anwer, A., 30 Dec 2020, IPC No. G01N 21/ 64 A I, A61B 5/00, G01J 3/28, Patent No. AU2020308961, Priority date 27 Jun 2019, Priority No. AU2019902257
Research output: Patent

Cite this

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title = "Diagnosis and monitoring of neurodegenerative diseases",

abstract = "Disclosed is a method for diagnosing a neurodegenerative disease in a subject. The method comprises obtaining from the subject a sample comprising at least one live blood cell, and optionally isolating at least one live blood cell from the sample. The method further comprises generating one or more multispectral or hyperspectral images of the at least one cell, and analysing spectral characteristics of autofluorescence from the at least one cell. Also disclosed is a system configured to aid in the detection or diagnosis of a neurodegenerative disease. Also disclosed is a method for selecting a subject for treatment for a neurodegenerative disease. Also disclosed is a method for monitoring the response of a subject to a therapeutic treatment for a neurodegenerative disease. Also disclosed is a protocol for monitoring the efficacy of a therapeutic treatment for a neurodegenerative disease.",

author = "Dominic Rowe and Ewa Goldys and Martin Gosnell and Ayad Anwer",

year = "2020",

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T1 - Diagnosis and monitoring of neurodegenerative diseases

AU - Rowe, Dominic

AU - Goldys, Ewa

AU - Gosnell, Martin

AU - Anwer, Ayad

PY - 2020/12/30

Y1 - 2020/12/30

N2 - Disclosed is a method for diagnosing a neurodegenerative disease in a subject. The method comprises obtaining from the subject a sample comprising at least one live blood cell, and optionally isolating at least one live blood cell from the sample. The method further comprises generating one or more multispectral or hyperspectral images of the at least one cell, and analysing spectral characteristics of autofluorescence from the at least one cell. Also disclosed is a system configured to aid in the detection or diagnosis of a neurodegenerative disease. Also disclosed is a method for selecting a subject for treatment for a neurodegenerative disease. Also disclosed is a method for monitoring the response of a subject to a therapeutic treatment for a neurodegenerative disease. Also disclosed is a protocol for monitoring the efficacy of a therapeutic treatment for a neurodegenerative disease.

AB - Disclosed is a method for diagnosing a neurodegenerative disease in a subject. The method comprises obtaining from the subject a sample comprising at least one live blood cell, and optionally isolating at least one live blood cell from the sample. The method further comprises generating one or more multispectral or hyperspectral images of the at least one cell, and analysing spectral characteristics of autofluorescence from the at least one cell. Also disclosed is a system configured to aid in the detection or diagnosis of a neurodegenerative disease. Also disclosed is a method for selecting a subject for treatment for a neurodegenerative disease. Also disclosed is a method for monitoring the response of a subject to a therapeutic treatment for a neurodegenerative disease. Also disclosed is a protocol for monitoring the efficacy of a therapeutic treatment for a neurodegenerative disease.

M3 - Patent

M1 - WO2020257861

Y2 - 2020/06/26

ER -

Diagnosis and monitoring of neurodegenerative diseases

Abstract

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