Dielectrophoretic manipulation and separation of particles in an S-shaped microchannel with hurdles

Ming Li, Shunbo Li, Weihua Li, Weijia Wen, Gursel Alici

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

This paper presents a novel dielectrophoresis (DEP)-based microfluidic device, which incorporates multiple round hurdles within an S-shaped curved microchannel for continuous manipulation and separation of microparticles. Local nonuniform electric fields are induced by means of both constricted gaps formed between hurdles and outer channel wall, and variable current lengths in curved sections with equal width. Under the effect of negative DEP, particles will be directed away from either inner wall or hurdle edge, as they transport throughout the microchannel electrokinetically. Both experiment and numerical simulation were conducted, the results of which showed that fix-sized (i.e. 10 or 15 μm) polystyrene (PS) particles could be successfully switched, directed and focused by adjusting applied voltages at inlet and outlets, and size-based separation of 10 and 15 μm particles was achieved with a careful selection of applied voltages. Compared to other microchannel designs that make use of either obstacle or curvature individually for inhomogeneous electric fields, this design offers advantages such as improved controllability over particle motion, lower requirement of applied voltage, reduced fouling and particle adhesion, etc.
Original languageEnglish
Title of host publication2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics
Subtitle of host publicationMechatronics for Human Wellbeing
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages362-366
Number of pages5
ISBN (Electronic)9781467353205, 9781467353182
ISBN (Print)9781467353199
DOIs
Publication statusPublished - 2013
Externally publishedYes
Event2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics: Mechatronics for Human Wellbeing - Wollongong, Australia
Duration: 9 Jul 201312 Jul 2013

Publication series

Name
ISSN (Print)2159-6247
ISSN (Electronic)2159-6255

Conference

Conference2013 IEEE/ASME International Conference on Advanced Intelligent Mechatronics
CountryAustralia
CityWollongong
Period9/07/1312/07/13

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