TY - JOUR
T1 - Disgust elevates core body temperature and up-regulates certain oral immune markers
AU - Stevenson, Richard J.
AU - Hodgson, Deborah
AU - Oaten, Megan J.
AU - Moussavi, Mahta
AU - Langberg, Rebekah
AU - Case, Trevor I.
AU - Barouei, Javad
PY - 2012/10
Y1 - 2012/10
N2 - Recent findings suggest that disgust can activate particular aspects of the immune system. In this study we examine whether disgust can also elevate core body temperature (BT), a further feature of an immune response to disease. In addition, we also examined whether food based disgust - a core eliciting stimulus - may be a more potent immune stimulus than non-food based disgust. Healthy males were randomly assigned to view one of four sets of images - food disgust, non-food disgust, food control and negative emotion control. Measures of BT, salivary immune and related markers, and self-report data, were collected before, and at two time points after image viewing. Disgust elevated BT relative to the negative emotion control condition, as did food images. Different mechanisms appeared to account for these effects on BT, with higher initial levels of Tumor Necrosis Factor alpha (TNF-a) and disgust, predictive of BT increases in the disgust conditions. Disgust also increased TNF-a, and albumin levels, relative to the control conditions. Type of disgust exerted little effect. These findings further support the idea that disgust impacts upon immune function, and that disgust serves primarily a disease avoidance function.
AB - Recent findings suggest that disgust can activate particular aspects of the immune system. In this study we examine whether disgust can also elevate core body temperature (BT), a further feature of an immune response to disease. In addition, we also examined whether food based disgust - a core eliciting stimulus - may be a more potent immune stimulus than non-food based disgust. Healthy males were randomly assigned to view one of four sets of images - food disgust, non-food disgust, food control and negative emotion control. Measures of BT, salivary immune and related markers, and self-report data, were collected before, and at two time points after image viewing. Disgust elevated BT relative to the negative emotion control condition, as did food images. Different mechanisms appeared to account for these effects on BT, with higher initial levels of Tumor Necrosis Factor alpha (TNF-a) and disgust, predictive of BT increases in the disgust conditions. Disgust also increased TNF-a, and albumin levels, relative to the control conditions. Type of disgust exerted little effect. These findings further support the idea that disgust impacts upon immune function, and that disgust serves primarily a disease avoidance function.
UR - http://www.scopus.com/inward/record.url?scp=84865663680&partnerID=8YFLogxK
U2 - 10.1016/j.bbi.2012.07.010
DO - 10.1016/j.bbi.2012.07.010
M3 - Article
VL - 26
SP - 1160
EP - 1168
JO - Brain, Behavior, and Immunity
JF - Brain, Behavior, and Immunity
SN - 0889-1591
IS - 7
ER -