Diversity and evolution of phycobilisomes in marine Synechococcus spp.

A comparative genomics study

Christophe Six, Jean Claude Thomas, Laurence Garczarek, Martin Ostrowski, Alexis Dufresne, Nicolas Blot, David J. Scanlan, Frédéric Partensky*

*Corresponding author for this work

Research output: Contribution to journalArticle

158 Citations (Scopus)

Abstract

Background: Marine Synechococcus owe their specific vivid color (ranging from blue-green to orange) to their large extrinsic antenna complexes called phycobilisomes, comprising a central allophycocyanin core and rods of variable phycobiliprotein composition. Three major pigment types can be defined depending on the major phycobiliprotein found in the rods (phycocyanin, phycoerythrin I or phycoerythrin II). Among strains containing both phycoerythrins I and II, four subtypes can be distinguished based on the ratio of the two chromophores bound to these phycobiliproteins. Genomes of eleven marine Synechococcus strains recently became available with one to four strains per pigment type or subtype, allowing an unprecedented comparative genomics study of genes involved in phycobilisome metabolism. Results: By carefully comparing the Synechococcus genomes, we have retrieved candidate genes potentially required for the synthesis of phycobiliproteins in each pigment type. This includes linker polypeptides, phycobilin lyases and a number of novel genes of uncharacterized function. Interestingly, strains belonging to a given pigment type have similar phycobilisome gene complements and organization, independent of the core genome phylogeny (as assessed using concatenated ribosomal proteins). While phylogenetic trees based on concatenated allophycocyanin protein sequences are congruent with the latter, those based on phycocyanin and phycoerythrin notably differ and match the Synechococcus pigment types. Conclusion: We conclude that the phycobilisome core has likely evolved together with the core genome, while rods must have evolved independently, possibly by lateral transfer of phycobilisome rod genes or gene clusters between Synechococcus strains, either via viruses or by natural transformation, allowing rapid adaptation to a variety of light niches.

Original languageEnglish
Article numberR259
Pages (from-to)1-22
Number of pages22
JournalGenome Biology
Volume8
Issue number12
DOIs
Publication statusPublished - 5 Dec 2007
Externally publishedYes

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    Six, C., Thomas, J. C., Garczarek, L., Ostrowski, M., Dufresne, A., Blot, N., ... Partensky, F. (2007). Diversity and evolution of phycobilisomes in marine Synechococcus spp. A comparative genomics study. Genome Biology, 8(12), 1-22. [R259]. https://doi.org/10.1186/gb-2007-8-12-r259