Abstract
[Fe(1,10-phenanthroline)3]2+ is known to racemise in solution and DNA is known to shift the equilibrium point of the Δ/Λ[Fe(1,10-phenanthroline)3]2+ mixture from 50:50 to a position favouring a slight excess of the Δ enantiomer. In this paper it is shown that DNA catalyses the racemisation reaction, presumably by providing vibrational energy to species that bind in a less favoured mode for that enantiomer. The racemisation of [Co(1,10-phenanthroline)3]3+, however, is not enhanced by DNA unless [Co(1,10-phenanthroline)3]2+ is also added to the solution. In this case, the DNA acts as a template to facilitate the CoII ⇄ CoIII electron transfer. Racemisation occurs while the [Co(1,10-phenanthroline)3]n+ is in the labile CoII form.
Original language | English |
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Pages (from-to) | 49-53 |
Number of pages | 5 |
Journal | European Journal of Inorganic Chemistry |
Issue number | 1 |
Publication status | Published - 2002 |
Externally published | Yes |
Keywords
- Bioinorganic chemistry
- Circular dichroism
- Coordination chemistry
- Racemisation