DNA degradation and protein peroxidation in cells exposed to hydroxyl free radicals

Juan Du, Janusz M. Gebicki*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)

    Abstract

    The kinetics of DNA and protein damage in two lines of cultured cells exposed to radiation-generated hydroxyl free radicals were measured. The results show that DNA damage is a relatively late event, preceded by the formation of protein hydroperoxides which may play a role in the degradation of the DNA.

    Original languageEnglish
    Pages (from-to)329-331
    Number of pages3
    JournalRedox Report
    Volume7
    Issue number5
    DOIs
    Publication statusPublished - 2002

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