Do personality disorders predict negative treatment outcome in obsessive-compulsive disorders? A prospective 6-month follow-up study

Susanne Fricke*, Steffen Moritz, Burghard Andresen, Dirk Jacobsen, Martin Kloss, Michael Rufer, Iver Hand

*Corresponding author for this work

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Background. - Comorbid personality disorders (PDs) are discussed as risk factors for a negative treatment outcome in obsessive-compulsive disorder (OCD). However, studies published so far have produced conflicting results. The present study examined whether PDs affect treatment outcome in patients with OCD. Method. - The treatment sample consisted of 55 patients with OCD who were consecutively referred to a Behaviour Therapy Unit for an in-patient or day-clinic treatment. Treatment consisted of an individualised and multimodal cognitive behaviour therapy (CBT, with or without antidepressive medication). Measurements were taken prior and after treatment and 6-month after admission. Results. - A large percentage of patients benefited from treatment irrespective of the presence of a PD and were able to maintain their improvement at follow-up. Duration of treatment was not prolonged in OCD patients with concomitant Axis II disorders. However, some specific personality traits (schizotypal, passive-aggressive) were baseline determinants for later treatment failure at trend level. Conclusions. - Results are encouraging for therapists working with patients co-diagnosed with Axis II disorders since these patients are not necessarily non-responders. The results stress the importance of a specifically tailored treatment approach based on an individual case formulation in OCD patients with complex symptomatology and comorbid Axis II disorders.

Original languageEnglish
Pages (from-to)319-324
Number of pages6
JournalEuropean Psychiatry
Volume21
Issue number5
DOIs
Publication statusPublished - Jul 2006
Externally publishedYes

Keywords

  • Comorbid personality disorder
  • Multimodal cognitive behaviour therapy
  • Obsessive-compulsive disorder
  • Outcome

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