Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis

Medicine & Life Sciences

• 4,6-dinitro-o-cresol 100%
• Trichomonas vaginalis 94%
• Alcohol Dehydrogenase 90%
• Metronidazole 79%
• Oxidoreductases 64%
• Down-Regulation 49%
• Tinidazole 21%
• Thioredoxin-Disulfide Reductase 20%
• Trichomonas Infections 19%
• Nitroimidazoles 10%
• Oxygen 9%
• Vaginitis 9%
• Urethritis 9%
• Acetaldehyde 9%
• Electrophoresis, Gel, Two-Dimensional 8%
• Stillbirth 8%
• Enzymes 7%
• Hydrogen Peroxide 7%
• Treatment Failure 6%
• Parasites 5%
• Pharmaceutical Preparations 5%
• Proteins 2%

Agriculture & Biology

• Trichomonas vaginalis 98%
• metronidazole 91%
• flavins 85%
• alcohol dehydrogenase 78%
• tinidazole 24%
• trichomoniasis 21%
• thioredoxins 16%
• vaginitis 11%
• nitroimidazoles 10%
• oxygen 9%
• drugs 9%
• fetal death 8%
• induced resistance 8%
• acetaldehyde 8%
• cross resistance 8%
• two-dimensional gel electrophoresis 7%
• hydrogen peroxide 6%
• protein synthesis 5%
• parasites 4%
• enzyme activity 4%
• enzymes 3%