Dynamic contrast-enhanced MR imaging of musculoskeletal tumors: Basic principles and clinical applications

Koenraad L. Verstraele*, Henk Jan Van Der Woude, Pancras C W Hogendoorn, Yves De Deene, Marc Kunnen, Johannes L. Bloem

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

115 Citations (Scopus)

Abstract

The purpose of this article is to review the basic principles and clinical applications of dynamic contrast-enhanced MRI in the musculoskeletal system. This method of physiologic imaging provides clinically useful information by depicting tissue vascularization and perfusion, capillary permeability, and composition of the interstitial space. Different imaging, evaluation, and postprocessing techniques are described. The most important applications in the musculoskeletal system are identification of areas of viable tumor for biopsy, tissue characterization, and monitoring of preoperative chemotherapy. Practical guidelines for performing a dynamic contrast-enhanced MR examination are proposed.

Original languageEnglish
Pages (from-to)311-321
Number of pages11
JournalJournal of Magnetic Resonance Imaging
Volume6
Issue number2
Publication statusPublished - Mar 1996
Externally publishedYes

Keywords

  • Bones, MR
  • Dynamic imaging
  • Gadolinium
  • Image processing
  • Magnetic resonance (MR), contrast enhancement
  • Soft tissues, MR

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