Early inflammatory reaction after rotator cuff repair with a porcine small intestine submucosal implant

A report of 4 cases

Hilary L. Malcarney, Fiona Bonar, G. A C Murrell*

*Corresponding author for this work

Research output: Contribution to journalArticle

133 Citations (Scopus)

Abstract

Background: Porcine small intestine submucosal grafts have been successful in enhancing soft tissue repair, as demonstrated by animal studies. Currently, there are no reports of the use of such implants in human rotator cuff repair. Study Design: Case series; Level of evidence, 4. Methods: Over a 6-month period, 25 patients underwent rotator cuff repair by one surgeon using the Restore Orthobiologic Implant to augment the repaired tendon or fill a defect. Results: Four of 25 patients experienced an overt inflammatory reaction at a mean of 13 days postoperatively. All patients underwent open irrigation and debridement of the rotator cuff and porcine small intestine submucosal implant. Conclusion: Porcine small intestine submucosal implants should be used in rotator cuff surgery with the awareness that a non-specific inflammatory reaction can occur in the early postoperative period. This inflammatory reaction may cause breakdown of the repair. Further studies are needed to further characterize the reaction and determine which patients are susceptible.

Original languageEnglish
Pages (from-to)907-911
Number of pages5
JournalAmerican Journal of Sports Medicine
Volume33
Issue number6
DOIs
Publication statusPublished - Jun 2005
Externally publishedYes

Keywords

  • Inflammatory reaction
  • Porcine small intestine submucosal (SIS) implant
  • Rotator cuff repair
  • Shoulder

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