Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial

Yahya Shehabi*, Ary Serpa Neto, Belinda D. Howe, Rinaldo Bellomo, Yaseen M. Arabi, Michael Bailey, Frances E. Bass, Suhaini Bin Kadiman, Colin J. McArthur, Michael C. Reade, Ian M. Seppelt, Jukka Takala, Matt P. Wise, Steve A. Webb, The SPICE III study investigators

*Corresponding author for this work

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