Eccrine porocarcinoma

a case report with light microscopy and ultrastructure

Jennifer J. Turner*, L. Maxwell, G. A. Bursle

*Corresponding author for this work

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

A case of eccrine porocarcinoma in a 63-yr-old man is reported. There was a 10 yr history of an abdominal skin lesion which recurred after cautery and metastasized to skin and abdominal lymph nodes. Histologically, the primary tumour was composed of small squamoid cells with ductal lumina. There was intraepidermal nesting spread and an invasive dermal component. Formation of intracytoplasmic lumina in cells with squamoid features, best seen on electron microscopy, pointed towards poral differentiation and was a useful diagnostic feature which persisted in the less well differentiated metastases. The role of hidroacanthoma simplex as a possible preinvasive precursor lesion is discussed. The differential diagnosis from other skin tumours is described. The literature is reviewed. Despite their sometimes innocuous histological appearance, eccrine porocarcinomas are aggressive lesions which require wide local excision of the primary site and consideration of regional lymph node dissection.

Original languageEnglish
Pages (from-to)469-475
Number of pages7
JournalPathology
Volume14
Issue number4
DOIs
Publication statusPublished - 1 Jan 1982
Externally publishedYes

Keywords

  • Eccrine porocarcinoma
  • Malignant hidroacanthoma simplex
  • Sweat gland neoplasms

Fingerprint Dive into the research topics of 'Eccrine porocarcinoma: a case report with light microscopy and ultrastructure'. Together they form a unique fingerprint.

  • Cite this