Echinoderm immunity

L. Courtney Smith*, Julie Ghosh, Katherine M. Buckley, Lori A. Clow, Nolwenn M. Dheilly, Tor Haug, John H. Henson, Chun Li, Cheng Man Lun, Audrey J. Majeske, Valeria Matranga, Sham V. Nair, Jonathan P. Rast, David A. Raftos, Mattias Roth, Sandro Sacchi, Catherine S. Schrankel, Klara Stensvåg

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

109 Citations (Scopus)

Abstract

A survey for immune genes in the genome for the purple sea urchin has shown that the immune system is complex and sophisticated. By inference, immune responses of all echinoderms may be similar. The immune system is mediated by several types of coelomocytes that are also useful as sensors of environmental stresses. There are a number of large gene families in the purple sea urchin genome that function in immunity and of which at least one appears to employ novel approaches for sequence diversification. Echinoderms have a simpler complement system, a large set of lectin genes and a number of antimicrobial peptides. Profiling the immune genes expressed by coelomocytes and the proteins in the coelomic fluid provide detailed information about immune functions in the sea urchin. The importance of echinoderms in maintaining marine ecosystem stability and the disastrous effects of their removal due to disease will require future collaborations between ecologists and immunologists working towards understanding and preserving marine habitats.

Original languageEnglish
Title of host publicationInvertebrate Immunity
EditorsKenneth Söderhäll
Place of PublicationNew York
PublisherSpringer, Springer Nature
Pages260-301
Number of pages42
Volume708
ISBN (Electronic)9781441980595
ISBN (Print)9781441980588
DOIs
Publication statusPublished - 2010

Publication series

NameAdvances in Experimental Medicine and Biology
Volume708
ISSN (Print)0065-2598

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  • Cite this

    Smith, L. C., Ghosh, J., Buckley, K. M., Clow, L. A., Dheilly, N. M., Haug, T., ... Stensvåg, K. (2010). Echinoderm immunity. In K. Söderhäll (Ed.), Invertebrate Immunity (Vol. 708, pp. 260-301). (Advances in Experimental Medicine and Biology; Vol. 708). New York: Springer, Springer Nature. https://doi.org/10.1007/978-1-4419-8059-5_14