TY - JOUR
T1 - EcoCyc
T2 - a comprehensive database resource for Escherichia coli
AU - Keseler, Ingrid M.
AU - Collado-Vides, Julio
AU - Gama-Castro, Socorro
AU - Ingraham, John
AU - Paley, Suzanne
AU - Paulsen, Ian T.
AU - Peralta-Gil, Martín
AU - Karp, Peter D.
PY - 2005/1/1
Y1 - 2005/1/1
N2 - The EcoCyc database (http://EcoCyc.org/) is a comprehensive source of information on the biology of the prototypical model organism Escherichia coli K12. The mission for EcoCyc is to contain both computable descriptions of, and detailed comments describing, all genes, proteins, pathways and molecular interactions in E.coli. Through ongoing manual curation, extensive information such as summary comments, regulatory information, literature citations and evidence types has been extracted from 8862 publications and added to Version 8.5 of the EcoCyc database. The EcoCyc database can be accessed through a World Wide Web interface, while the down-loadable Pathway Tools software and data files enable computational exploration of the data and provide enhanced querying capabilities that web interfaces cannot support. For example, EcoCyc contains carefully curated information that can be used as training sets for bioinformatics prediction of entities such as promoters, operons, genetic networks, transcription factor binding sites, metabolic pathways, functionally related genes, protein complexes and protein-ligand interactions.
AB - The EcoCyc database (http://EcoCyc.org/) is a comprehensive source of information on the biology of the prototypical model organism Escherichia coli K12. The mission for EcoCyc is to contain both computable descriptions of, and detailed comments describing, all genes, proteins, pathways and molecular interactions in E.coli. Through ongoing manual curation, extensive information such as summary comments, regulatory information, literature citations and evidence types has been extracted from 8862 publications and added to Version 8.5 of the EcoCyc database. The EcoCyc database can be accessed through a World Wide Web interface, while the down-loadable Pathway Tools software and data files enable computational exploration of the data and provide enhanced querying capabilities that web interfaces cannot support. For example, EcoCyc contains carefully curated information that can be used as training sets for bioinformatics prediction of entities such as promoters, operons, genetic networks, transcription factor binding sites, metabolic pathways, functionally related genes, protein complexes and protein-ligand interactions.
UR - http://www.scopus.com/inward/record.url?scp=13444262374&partnerID=8YFLogxK
U2 - 10.1093/nar/gki108
DO - 10.1093/nar/gki108
M3 - Article
C2 - 15608210
AN - SCOPUS:13444262374
SN - 0305-1048
VL - 33
SP - D334-D337
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - DATABASE ISS.
ER -