fusing model organism databases with systems biology

Ingrid M. Keseler*, Amanda Mackie, Martin Peralta-Gil, Alberto Santos-Zavaleta, Socorro Gama-Castro, César Bonavides-Martínez, Carol Fulcher, Araceli M. Huerta, Anamika Kothari, Markus Krummenacker, Mario Latendresse, Luis Muñiz-Rascado, Quang Ong, Suzanne Paley, Imke Schröder, Alexander G. Shearer, Pallavi Subhraveti, Mike Travers, Deepika Weerasinghe, Verena Weiss & 4 others Julio Collado-Vides, Robert P. Gunsalus, Ian Paulsen, Peter D. Karp

*Corresponding author for this work

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    EcoCyc ( is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.

    Original languageEnglish
    Pages (from-to)D605-D612
    Number of pages8
    JournalNucleic Acids Research
    Issue numberD1
    Publication statusPublished - 1 Jan 2013

    Bibliographical note

    Electronic version of article originally published in Nucleic Acids Research, Oxford University Press Archived with the permission of the author and according to publisher conditions. For further information see

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    Keseler, I. M., Mackie, A., Peralta-Gil, M., Santos-Zavaleta, A., Gama-Castro, S., Bonavides-Martínez, C., ... Karp, P. D. (2013). EcoCyc: fusing model organism databases with systems biology. Nucleic Acids Research, 41(D1), D605-D612.