Effectiveness and efficiency of pre-operative anaemia management with intravenous iron

The quantitative objective is to identify the effectiveness of intravenous iron administration on the correction of iron deficiency anaemia in the perioperative setting.
More specifically, the objectives are to identify the effectiveness of iron infusion on the rate of red blood cell (RBC) transfusion and incidence of transfusion related co morbidities such as postoperative infection, immunological morbidity and mortality. In addition changes in functional capacity that could impact on quality of life.
The economic objective of this review is to identify the cost aspects of anaemia management.
More specifically, the objectives are to identify the evidence of cost benefits on pre-operative anaemia correction and the potential for cost savings on blood products and the indirect cost savings on transfusion related adverse effects.