TY - JOUR
T1 - Effects of fluid structure interaction in a three dimensional model of the spinal subarachnoid space
AU - Cheng, Shaokoon
AU - Fletcher, David
AU - Hemley, Sarah
AU - Stoodley, Marcus
AU - Bilston, Lynne
N1 - Corrigendum can be found in Journal of Biomechanics volume 47(14), p 3590, https://doi.org/10.1016/j.jbiomech.2014.09.024
PY - 2014/8/22
Y1 - 2014/8/22
N2 - It is unknown whether spinal cord motion has a significant effect on cerebrospinal fluid (CSF) pressure and therefore the importance of including fluid structure interaction (FSI) in computational fluid dynamics models (CFD) of the spinal subarachnoid space (SAS) is unclear. This study aims to determine the effects of FSI on CSF pressure and spinal cord motion in a normal and in a stenosis model of the SAS. A three-dimensional patient specific model of the SAS and spinal cord were constructed from MR anatomical images and CSF flow rate measurements obtained from a healthy human being. The area of SAS at spinal level T4 was constricted by 20% to represent the stenosis model. FSI simulations in both models were performed by running ANSYS CFX and ANSYS Mechanical in tandem. Results from this study show that the effect of FSI on CSF pressure is only about 1% in both the normal and stenosis models and therefore show that FSI has a negligible effect on CSF pressure.
AB - It is unknown whether spinal cord motion has a significant effect on cerebrospinal fluid (CSF) pressure and therefore the importance of including fluid structure interaction (FSI) in computational fluid dynamics models (CFD) of the spinal subarachnoid space (SAS) is unclear. This study aims to determine the effects of FSI on CSF pressure and spinal cord motion in a normal and in a stenosis model of the SAS. A three-dimensional patient specific model of the SAS and spinal cord were constructed from MR anatomical images and CSF flow rate measurements obtained from a healthy human being. The area of SAS at spinal level T4 was constricted by 20% to represent the stenosis model. FSI simulations in both models were performed by running ANSYS CFX and ANSYS Mechanical in tandem. Results from this study show that the effect of FSI on CSF pressure is only about 1% in both the normal and stenosis models and therefore show that FSI has a negligible effect on CSF pressure.
KW - spinal cord
KW - cerebrospinal fluid dynamics
KW - syringomyelia
UR - http://www.scopus.com/inward/record.url?scp=84905961282&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/record.url?scp=84922697231&partnerID=8YFLogxK
UR - https://doi.org/10.1016/j.jbiomech.2014.09.024
U2 - 10.1016/j.jbiomech.2014.04.027
DO - 10.1016/j.jbiomech.2014.04.027
M3 - Article
C2 - 25005435
AN - SCOPUS:84905961282
SN - 0021-9290
VL - 47
SP - 2826
EP - 2830
JO - Journal of Biomechanics
JF - Journal of Biomechanics
IS - 11
ER -