Efficacy of manipulation for non-specific neck pain of recent onset: Design of a randomised controlled trial

Andrew M. Leaver*, Kathryn M. Refshauge, Christopher G. Maher, Jane Latimer, Rob D. Herbert, Gwendolen Jull, James H. McAuley

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Background. Manipulation is a common treatment for non-specific neck pain. Neck manipulation, unlike gentler forms of manual therapy such as mobilisation, is associated with a small risk of serious neurovascular injury and can result in stroke or death. It is thought however, that neck manipulation provides better results than mobilisation where clinically indicated. There is long standing and vigorous debate both within and between the professions that use neck manipulation as well as the wider scientific community as to whether neck manipulation potentially does more harm than good. The primary aim of this study is to determine whether neck manipulation provides more rapid resolution of an episode of neck pain than mobilisation. Methods/Design. 182 participants with acute and sub-acute neck pain will be recruited from physiotherapy, chiropractic and osteopathy practices in Sydney, Australia. Participants will be randomly allocated to treatment with either manipulation or mobilisation. Randomisation will occur after the treating practitioner decides that manipulation is an appropriate treatment for the individual participant. Both groups will receive at least 4 treatments over 2 weeks. The primary outcome is number of days taken to recover from the episode of neck pain. Cox regression will be used to compare survival curves for time to recovery for the manipulation and mobilisation treatment groups. Discussion. This paper presents the rationale and design of a randomised controlled trial to compare the effectiveness of neck manipulation and neck mobilisation for acute and subacute neck pain.

Original languageEnglish
Article number18
Pages (from-to)1-5
Number of pages5
JournalBMC Musculoskeletal Disorders
Publication statusPublished - 2007
Externally publishedYes


Dive into the research topics of 'Efficacy of manipulation for non-specific neck pain of recent onset: Design of a randomised controlled trial'. Together they form a unique fingerprint.

Cite this