Efficient copper laser-pumped dye lasers for cancer photodynamic therapy

M. D. Ainsworth*, J. A. Piper

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

Abstract

Photodynamic therapy (PDT) based on the photosensitizer hematoporphyrin derivative (HPD) for treatment of human cancer tumors rests on the development of practical laser sources operating in the required spectral band (630 plus or minus 5 nm) with high average power ( greater than 1 W). Approaches to the development of lasers for HPD phototherapy based on the copper vapor laser and utilizing new dye laser techniques are reported. Initial experiments concentrated on studies of copper-laser-pumped dye amplifier systems locked to the lambda 627. 8-nm wavelength of the gold laser. Amplifier efficiencies and gain were measured as a function of injection power pump power, dye concentration, dye mixture, and solvent. Maximum conversion efficiencies of 30% and single-pass gains of 15-20 have been obtained.

Original languageEnglish
Title of host publicationConference on lasers and electro-optics: 26 April-1 May 1987, OSA/IEE, Baltimore, Maryland
Place of PublicationWashington, DC
PublisherOptical Society of America (OSA)
Pages102
Number of pages1
ISBN (Print)0936659491
Publication statusPublished - 1987

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