EHV-1 and EHV-4 infection in vaccinated mares and their foals

C. E. Foote, D. N. Love, J. R. Gilkerson, J. E. Wellington, J. M. Whalley

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    35 Citations (Scopus)


    A silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a Hunter Valley stud farm. Following the introduction of routine vaccination with an inactivated whole virus equine herpesvirus 1 (EHV-1) and equine herpesvirus 4 (EHV-4) vaccine in 1997, a subsequent study identified excretion of EHV-1 and EHV-4 in nasal swab samples tested by PCR from vaccinated mares and their unweaned, unvaccinated foals. The current sero-epidemiological investigation of vaccinated mares and their young foals found serological evidence of EHV-1 and EHV-4 infection in mares and foals in the first 5 weeks of life. The results further support that EHV-1 and EHV-4 circulate in vaccinated populations of mares and their unweaned foals and confirms the continuation of the cycle of EHV-1 and EHV-4 infection.
    Original languageEnglish
    Pages (from-to)41-46
    Number of pages6
    JournalVeterinary Immunology and Immunopathology
    Issue number1-2
    Publication statusPublished - 2006


    • horse
    • equine herpesvirus 1
    • EHV-1
    • EHV-4
    • vaccination
    • ELISA antibody


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