EHV-1 and EHV-4 infection in vaccinated mares and their foals

C. E. Foote, D. N. Love, J. R. Gilkerson, J. E. Wellington, J. M. Whalley

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Abstract

A silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a Hunter Valley stud farm. Following the introduction of routine vaccination with an inactivated whole virus equine herpesvirus 1 (EHV-1) and equine herpesvirus 4 (EHV-4) vaccine in 1997, a subsequent study identified excretion of EHV-1 and EHV-4 in nasal swab samples tested by PCR from vaccinated mares and their unweaned, unvaccinated foals. The current sero-epidemiological investigation of vaccinated mares and their young foals found serological evidence of EHV-1 and EHV-4 infection in mares and foals in the first 5 weeks of life. The results further support that EHV-1 and EHV-4 circulate in vaccinated populations of mares and their unweaned foals and confirms the continuation of the cycle of EHV-1 and EHV-4 infection.
Original languageEnglish
Pages (from-to)41-46
Number of pages6
JournalVeterinary immunology and immunopathology
Volume111
Issue number1-2
DOIs
Publication statusPublished - 2006

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Keywords

  • horse
  • equine herpesvirus 1
  • EHV-1
  • EHV-4
  • vaccination
  • ELISA antibody

Cite this

Foote, C. E., Love, D. N., Gilkerson, J. R., Wellington, J. E., & Whalley, J. M. (2006). EHV-1 and EHV-4 infection in vaccinated mares and their foals. Veterinary immunology and immunopathology, 111(1-2), 41-46. https://doi.org/10.1016/j.vetimm.2006.01.007