Electrical conductivity imaging of lower extremities using MREIT: Postmortem swine and in vivo human experiments

Eung Je Woo, Hyung Joong Kim, Atul S. Minhas, Young Tae Kim, Woo Chul Jeong, O. Jung Kwon

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionpeer-review

5 Citations (Scopus)

Abstract

Cross-sectional conductivity images of lower extremities were reconstructed using Magnetic Resonance Electrical Impedance Tomography (MREIT) techniques. Carbon-hydrogel electrodes were adopted for postmortem swine and in vivo human imaging experiments. Due to their large surface areas and good contacts on the skin, we could inject as much as 10 mA into the lower extremities of human subjects without producing a painful sensation. Using a 3T MREIT system, we first performed a series of postmortem swine experiments and produced high-resolution conductivity images of swine legs. Validating the experimental protocol for the lower extremities, we revised it for the following human experiments. After the review of the Institutional Review Board (IRB), we conducted our first MREIT experiments of human subjects using the same 3T MREIT system. Collecting magnetic flux density data inside lower extremities subject to multiple injection currents, we reconstructed cross-sectional conductivity images using the harmonic Bz algorithm. The conductivity images very well distinguished different parts of muscles inside the lower extremities. The outermost fatty layer was clearly shown in each conductivity image. We could observe severe noise in the outer layer of the bones primarily due to the MR signal void phenomenon there. Reconstructed conductivity images indicated that the internal regions of the bones have relatively high conductivity values. Future study is desired in terms of the conductivity image reconstruction algorithm to improve the image quality. Further human imaging experiments are planned and being conducted to produce high-resolution conductivity images from different parts of the human body.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages5830-5833
Number of pages4
ISBN (Print)9781424418152
DOIs
Publication statusPublished - 2008
Externally publishedYes
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 20 Aug 200825 Aug 2008

Conference

Conference30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period20/08/0825/08/08

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