Enantiopurification by co-crystallization within cyclodextrin metal–organic framework

Masoud Kazem-Rostami; Pardis Shirdast; Kalidas Mainali

doi:10.3390/cryst14060568

Enantiopurification by co-crystallization within cyclodextrin metal–organic framework

Masoud Kazem-Rostami^*, Pardis Shirdast, Kalidas Mainali

^*Corresponding author for this work

School of Natural Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

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Abstract

Tröger’s base analogs (TBAs) and their derivatives are versatile, Λ-shaped, tetracyclic chiral building blocks utilized in numerous fields of research. Although various methods for the enantiopurification of TBAs have been demonstrated in the literature, none has achieved it with the use of metal–organic frameworks (MOFs). This investigation introduces a convenient and scalable method to obtain enantiopure TBAs with the formation and digestion of a chiral MOF composed of fully recoverable and non-hazardous starting materials, namely, cyclodextrin-based metal–organic framework (CD-MOF).

Original language	English
Article number	568
Pages (from-to)	1-11
Number of pages	11
Journal	Crystals
Volume	14
Issue number	6
DOIs	https://doi.org/10.3390/cryst14060568
Publication status	Published - Jun 2024

Bibliographical note

© 2024 by the authors. Licensee MDPI, Basel, Switzerland. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

chirality
co-crystallization
enantiopurification
optical purity

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10.3390/cryst14060568Licence: CC BY

Publisher version (open access)Final published version, 3.29 MBLicence: CC BY

Cite this

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AU - Mainali, Kalidas

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KW - optical purity

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Enantiopurification by co-crystallization within cyclodextrin metal–organic framework

Abstract

Bibliographical note

Keywords

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