Endemic goitre in Central China caused by excessive iodine intake

Li Mu; Qu Chengyi; Qian Qidong; Jia Qingzhen; Creswell J. Eastman; John K. Collins; Liu Derun; Zhang Peiying; Zhang Chunde; Wang Huaixing; Steven C. Boyages; James J. Jupp; Glen F. Maberly

doi:10.1016/S0140-6736(87)90838-5

Endemic goitre in Central China caused by excessive iodine intake

Li Mu, Qu Chengyi, Qian Qidong, Jia Qingzhen, Creswell J. Eastman, John K. Collins, Liu Derun, Zhang Peiying, Zhang Chunde, Wang Huaixing, Steven C. Boyages, James J. Jupp, Glen F. Maberly

Research output: Contribution to journal › Short survey › peer-review

92 Citations (Scopus)

Abstract

Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 μg/1. Goitres were present in 65% (n = 120) and 15.4% (n=51), respectively. All children in both groups were clinically euthyroid and neurologically normal. Growth measurements and intellectual performance were similar in the two groups. Children from the high-iodine village had a lower mean serum triiodothyronine and higher serum free thyroxine and serum thyroid-stimulating hormone concentrations than the children from the control village. 2 cases of overt hypothyroidism were detected in the high-iodine village.

Original language	English
Pages (from-to)	257-259
Number of pages	3
Journal	The Lancet
Volume	330
Issue number	8553
DOIs	https://doi.org/10.1016/S0140-6736(87)90838-5
Publication status	Published - 1 Aug 1987

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title = "Endemic goitre in Central China caused by excessive iodine intake",

abstract = "Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 μg/1. Goitres were present in 65\% (n = 120) and 15.4\% (n=51), respectively. All children in both groups were clinically euthyroid and neurologically normal. Growth measurements and intellectual performance were similar in the two groups. Children from the high-iodine village had a lower mean serum triiodothyronine and higher serum free thyroxine and serum thyroid-stimulating hormone concentrations than the children from the control village. 2 cases of overt hypothyroidism were detected in the high-iodine village.",

author = "Li Mu and Qu Chengyi and Qian Qidong and Jia Qingzhen and Eastman, \{Creswell J.\} and Collins, \{John K.\} and Liu Derun and Zhang Peiying and Zhang Chunde and Wang Huaixing and Boyages, \{Steven C.\} and Jupp, \{James J.\} and Maberly, \{Glen F.\}",

year = "1987",

month = aug,

day = "1",

doi = "10.1016/S0140-6736(87)90838-5",

language = "English",

volume = "330",

pages = "257--259",

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number = "8553",

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TY - JOUR

T1 - Endemic goitre in Central China caused by excessive iodine intake

AU - Mu, Li

AU - Chengyi, Qu

AU - Qidong, Qian

AU - Qingzhen, Jia

AU - Eastman, Creswell J.

AU - Collins, John K.

AU - Derun, Liu

AU - Peiying, Zhang

AU - Chunde, Zhang

AU - Huaixing, Wang

AU - Boyages, Steven C.

AU - Jupp, James J.

AU - Maberly, Glen F.

PY - 1987/8/1

Y1 - 1987/8/1

N2 - Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 μg/1. Goitres were present in 65% (n = 120) and 15.4% (n=51), respectively. All children in both groups were clinically euthyroid and neurologically normal. Growth measurements and intellectual performance were similar in the two groups. Children from the high-iodine village had a lower mean serum triiodothyronine and higher serum free thyroxine and serum thyroid-stimulating hormone concentrations than the children from the control village. 2 cases of overt hypothyroidism were detected in the high-iodine village.

AB - Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 μg/1. Goitres were present in 65% (n = 120) and 15.4% (n=51), respectively. All children in both groups were clinically euthyroid and neurologically normal. Growth measurements and intellectual performance were similar in the two groups. Children from the high-iodine village had a lower mean serum triiodothyronine and higher serum free thyroxine and serum thyroid-stimulating hormone concentrations than the children from the control village. 2 cases of overt hypothyroidism were detected in the high-iodine village.

UR - https://www.scopus.com/pages/publications/0023213652

U2 - 10.1016/S0140-6736(87)90838-5

DO - 10.1016/S0140-6736(87)90838-5

M3 - Short survey

C2 - 2886725

AN - SCOPUS:0023213652

SN - 0140-6736

VL - 330

SP - 257

EP - 259

JO - The Lancet

JF - The Lancet

IS - 8553

ER -

Endemic goitre in Central China caused by excessive iodine intake

Abstract

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