Endobronchial deposits of chronic lymphocytic leukemia - an unusual cause of central airway obstruction

Miranda Maw*, Michael Harvey, Zinta Harrington, Melissa Baraket, Renn Montgomery, Jonathan Williamson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
1 Downloads (Pure)

Abstract

A 66-year-old woman with a background of chronic lymphocytic leukemia (CLL) was admitted to the hospital on several occasions with recurrent episodes of community-acquired pneumonia. Computed tomography and bronchoscopy revealed multiple obstructing endobronchial polyps. Post-obstructive pneumonia together with immunoglobulin G deficiency was considered the most likely cause of these recurrent infections. Bronchoscopy was performed for removal of the critically obstructing lesions. Histopathology revealed replacement of bronchial mucosa with CLL deposits. Despite a brief window of infection-free survival following therapy, she remained susceptible to pneumonia with further hospital admissions and eventually died from her disease.

Original languageEnglish
Pages (from-to)41-43
Number of pages3
JournalRespirology Case Reports
Volume3
Issue number2
DOIs
Publication statusPublished - Jun 2015
Externally publishedYes

Keywords

  • Bronchoscopy
  • Central airway obstruction
  • Chronic lymphocytic leukemia
  • Endobronchial deposits

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