Endoscopic transnasal decompression for management of basilar invagination in osteogenesis imperfecta

Mitchell A. Hansen, Melville J. da Cruz, Brian K. Owler*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Osteogenesis imperfecta (OI) is a disorder of bone development caused by a genetic dysfunction of collagen synthesis. Basilar invagination (BI) is an uncommon but serious complication of OI. Brainstem decompression in OI is undertaken in certain circumstances. Transoral-transpalatopharyngeal ventral decompression with posterior occipitocervical fusion has become the treatment of choice when required. This technical note Outlines a novel endoscopic transnasal approach for ventral decompression. The literature is reviewed and a strategy for the management of BI in patients with OI is Outlined.

Original languageEnglish
Pages (from-to)354-357
Number of pages4
JournalJournal of Neurosurgery: Spine
Issue number4
Publication statusPublished - Oct 2008
Externally publishedYes


  • basilar invagination
  • occipitocervical fusion
  • odontoidectomy
  • osteogenesis imperfecta
  • transnasal approach

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