Abstract
Background: Ascending aortic penetrating atherosclerotic ulcers (PAUs) are rare acute aortic syndromes, where guidelines recommend surgical repair. In surgically ineligible patients, endovascular repair has been described; however, data on management of postoperative complications are limited. Case Summary: A frail 75-year-old woman presented with dyspnea, 1 month after emergency endovascular repair of a ruptured ascending aortic PAU. Computed tomography aortography (CTA) demonstrated a late type IA endoleak with associated pseudoaneurysm. Given her prohibitive surgical risk, a staged approach was initially used by creating a scaffold with transcatheter aortic valve implantation and deployment of an atrial septal defect occluder across the pseudoaneurysm's neck, followed by patent foramen ovale occluder implantation, coil packing, and thrombin injection. This achieved complete endoleak exclusion and pseudoaneurysm sealing, confirmed on serial CTAs. The patient remains well after 1 year. Discussion: This is the first case of successful endovascular repair of a type IA endoleak and pseudoaneurysm, following endovascular repair of the ascending aorta. Take-Home Message: Complex ascending aortic complications can be managed endovascularly.
| Original language | English |
|---|---|
| Article number | 110003 |
| Number of pages | 8 |
| Journal | JACC: Case Reports |
| DOIs | |
| Publication status | Accepted/In press - 24 Jul 2026 |
| Externally published | Yes |
Bibliographical note
Crown Copyright 2026. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.Keywords
- acute aortic syndrome
- ascending aortic penetrating ulcer
- complex endovascular repair
- type IA endoleak
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