ENIGMA-Sleep: challenges, opportunities, and the road map

Masoud Tahmasian; André Aleman; Ole A. Andreassen; Zahra Arab; Marion Baillet; Francesco Benedetti; Tom Bresser; Joanna Bright; Michael W.L. Chee; Daphne Chylinski; Wei Cheng; Michele Deantoni; Martin Dresler; Simon B. Eickhoff; Claudia R. Eickhoff; Torbjørn Elvsåshagen; Jianfeng Feng; Jessica C. Foster-Dingley; Habib Ganjgahi; Hans J. Grabe; Nynke A. Groenewold; Tiffany C. Ho; Seung Bong Hong; Josselin Houenou; Benson Irungu; Neda Jahanshad; Habibolah Khazaie; Hosung Kim; Ekaterina Koshmanova; Desi Kocevska; Peter Kochunov; Oti Lakbila-Kamal; Jeanne Leerssen; Meng Li; Annemarie I. Luik; Vincenzo Muto; Justinas Narbutas; Gustav Nilsonne; Victoria S. O’Callaghan; Alexander Olsen; Ricardo S. Osorio; Sara Poletti; Govinda Poudel; Joyce E. Reesen; Liesbeth Reneman; Mathilde Reyt; Dieter Riemann; Ivana Rosenzweig; Masoumeh Rostampour; Amin Saberi; Julian Schiel; Christina Schmidt; Anouk Schrantee; Emma Sciberras; Tim J. Silk; Kang Sim; Hanne Smevik; Jair C. Soares; Kai Spiegelhalder; Dan J. Stein; Puneet Talwar; Sandra Tamm; Giana l. Teresi; Sofie L. Valk; Eus Van Someren; Gilles Vandewalle; Maxime Van Egroo; Henry Völzke; Martin Walter; Rick Wassing; Frederik D. Weber; Antoine Weihs; Lars Tjelta Westlye; Margaret J. Wright; Mon-Ju Wu; Nathalia Zak; Mojtaba Zarei

doi:10.1111/jsr.13347

ENIGMA-Sleep: challenges, opportunities, and the road map

Masoud Tahmasian^*, André Aleman, Ole A. Andreassen, Zahra Arab, Marion Baillet, Francesco Benedetti, Tom Bresser, Joanna Bright, Michael W.L. Chee, Daphne Chylinski, Wei Cheng, Michele Deantoni, Martin Dresler, Simon B. Eickhoff, Claudia R. Eickhoff, Torbjørn Elvsåshagen, Jianfeng Feng, Jessica C. Foster-Dingley, Habib Ganjgahi, Hans J. GrabeNynke A. Groenewold, Tiffany C. Ho, Seung Bong Hong, Josselin Houenou, Benson Irungu, Neda Jahanshad, Habibolah Khazaie, Hosung Kim, Ekaterina Koshmanova, Desi Kocevska, Peter Kochunov, Oti Lakbila-Kamal, Jeanne Leerssen, Meng Li, Annemarie I. Luik, Vincenzo Muto, Justinas Narbutas, Gustav Nilsonne, Victoria S. O’Callaghan, Alexander Olsen, Ricardo S. Osorio, Sara Poletti, Govinda Poudel, Joyce E. Reesen, Liesbeth Reneman, Mathilde Reyt, Dieter Riemann, Ivana Rosenzweig, Masoumeh Rostampour, Amin Saberi, Julian Schiel, Christina Schmidt, Anouk Schrantee, Emma Sciberras, Tim J. Silk, Kang Sim, Hanne Smevik, Jair C. Soares, Kai Spiegelhalder, Dan J. Stein, Puneet Talwar, Sandra Tamm, Giana l. Teresi, Sofie L. Valk, Eus Van Someren, Gilles Vandewalle, Maxime Van Egroo, Henry Völzke, Martin Walter, Rick Wassing, Frederik D. Weber, Antoine Weihs, Lars Tjelta Westlye, Margaret J. Wright, Mon-Ju Wu, Nathalia Zak, Mojtaba Zarei

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

18 Citations (Scopus)

Abstract

Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine.

Original language	English
Article number	e13347
Pages (from-to)	1-20
Number of pages	20
Journal	Journal of Sleep Research
Volume	30
Issue number	6
DOIs	https://doi.org/10.1111/jsr.13347
Publication status	Published - Dec 2021
Externally published	Yes

Keywords

ENIGMA consortium
large-scale collaboration
neurogenetics
neuroimaging
sleep

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10.1111/jsr.13347

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Tahmasian, M., Aleman, A., Andreassen, O. A., Arab, Z., Baillet, M., Benedetti, F., Bresser, T., Bright, J., Chee, M. W. L., Chylinski, D., Cheng, W., Deantoni, M., Dresler, M., Eickhoff, S. B., Eickhoff, C. R., Elvsåshagen, T., Feng, J., Foster-Dingley, J. C., Ganjgahi, H., ... Zarei, M. (2021). ENIGMA-Sleep: challenges, opportunities, and the road map. Journal of Sleep Research, 30(6), 1-20. Article e13347. https://doi.org/10.1111/jsr.13347

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title = "ENIGMA-Sleep: challenges, opportunities, and the road map",

abstract = "Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine.",

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author = "Masoud Tahmasian and Andr{\'e} Aleman and Andreassen, {Ole A.} and Zahra Arab and Marion Baillet and Francesco Benedetti and Tom Bresser and Joanna Bright and Chee, {Michael W.L.} and Daphne Chylinski and Wei Cheng and Michele Deantoni and Martin Dresler and Eickhoff, {Simon B.} and Eickhoff, {Claudia R.} and Torbj{\o}rn Elvs{\aa}shagen and Jianfeng Feng and Foster-Dingley, {Jessica C.} and Habib Ganjgahi and Grabe, {Hans J.} and Groenewold, {Nynke A.} and Ho, {Tiffany C.} and {Bong Hong}, Seung and Josselin Houenou and Benson Irungu and Neda Jahanshad and Habibolah Khazaie and Hosung Kim and Ekaterina Koshmanova and Desi Kocevska and Peter Kochunov and Oti Lakbila-Kamal and Jeanne Leerssen and Meng Li and Luik, {Annemarie I.} and Vincenzo Muto and Justinas Narbutas and Gustav Nilsonne and O{\textquoteright}Callaghan, {Victoria S.} and Alexander Olsen and Osorio, {Ricardo S.} and Sara Poletti and Govinda Poudel and Reesen, {Joyce E.} and Liesbeth Reneman and Mathilde Reyt and Dieter Riemann and Ivana Rosenzweig and Masoumeh Rostampour and Amin Saberi and Julian Schiel and Christina Schmidt and Anouk Schrantee and Emma Sciberras and Silk, {Tim J.} and Kang Sim and Hanne Smevik and Soares, {Jair C.} and Kai Spiegelhalder and Stein, {Dan J.} and Puneet Talwar and Sandra Tamm and Teresi, {Giana l.} and Valk, {Sofie L.} and {Van Someren}, Eus and Gilles Vandewalle and {Van Egroo}, Maxime and Henry V{\"o}lzke and Martin Walter and Rick Wassing and Weber, {Frederik D.} and Antoine Weihs and Westlye, {Lars Tjelta} and Wright, {Margaret J.} and Mon-Ju Wu and Nathalia Zak and Mojtaba Zarei",

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doi = "10.1111/jsr.13347",

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Tahmasian, M, Aleman, A, Andreassen, OA, Arab, Z, Baillet, M, Benedetti, F, Bresser, T, Bright, J, Chee, MWL, Chylinski, D, Cheng, W, Deantoni, M, Dresler, M, Eickhoff, SB, Eickhoff, CR, Elvsåshagen, T, Feng, J, Foster-Dingley, JC, Ganjgahi, H, Grabe, HJ, Groenewold, NA, Ho, TC, Bong Hong, S, Houenou, J, Irungu, B, Jahanshad, N, Khazaie, H, Kim, H, Koshmanova, E, Kocevska, D, Kochunov, P, Lakbila-Kamal, O, Leerssen, J, Li, M, Luik, AI, Muto, V, Narbutas, J, Nilsonne, G, O’Callaghan, VS, Olsen, A, Osorio, RS, Poletti, S, Poudel, G, Reesen, JE, Reneman, L, Reyt, M, Riemann, D, Rosenzweig, I, Rostampour, M, Saberi, A, Schiel, J, Schmidt, C, Schrantee, A, Sciberras, E, Silk, TJ, Sim, K, Smevik, H, Soares, JC, Spiegelhalder, K, Stein, DJ, Talwar, P, Tamm, S, Teresi, GL, Valk, SL, Van Someren, E, Vandewalle, G, Van Egroo, M, Völzke, H, Walter, M, Wassing, R, Weber, FD, Weihs, A, Westlye, LT, Wright, MJ, Wu, M-J, Zak, N & Zarei, M 2021, 'ENIGMA-Sleep: challenges, opportunities, and the road map', Journal of Sleep Research, vol. 30, no. 6, e13347, pp. 1-20. https://doi.org/10.1111/jsr.13347

TY - JOUR

T1 - ENIGMA-Sleep

T2 - challenges, opportunities, and the road map

AU - Tahmasian, Masoud

AU - Aleman, André

AU - Andreassen, Ole A.

AU - Arab, Zahra

AU - Baillet, Marion

AU - Benedetti, Francesco

AU - Bresser, Tom

AU - Bright, Joanna

AU - Chee, Michael W.L.

AU - Chylinski, Daphne

AU - Cheng, Wei

AU - Deantoni, Michele

AU - Dresler, Martin

AU - Eickhoff, Simon B.

AU - Eickhoff, Claudia R.

AU - Elvsåshagen, Torbjørn

AU - Feng, Jianfeng

AU - Foster-Dingley, Jessica C.

AU - Ganjgahi, Habib

AU - Grabe, Hans J.

AU - Groenewold, Nynke A.

AU - Ho, Tiffany C.

AU - Bong Hong, Seung

AU - Houenou, Josselin

AU - Irungu, Benson

AU - Jahanshad, Neda

AU - Khazaie, Habibolah

AU - Kim, Hosung

AU - Koshmanova, Ekaterina

AU - Kocevska, Desi

AU - Kochunov, Peter

AU - Lakbila-Kamal, Oti

AU - Leerssen, Jeanne

AU - Li, Meng

AU - Luik, Annemarie I.

AU - Muto, Vincenzo

AU - Narbutas, Justinas

AU - Nilsonne, Gustav

AU - O’Callaghan, Victoria S.

AU - Olsen, Alexander

AU - Osorio, Ricardo S.

AU - Poletti, Sara

AU - Poudel, Govinda

AU - Reesen, Joyce E.

AU - Reneman, Liesbeth

AU - Reyt, Mathilde

AU - Riemann, Dieter

AU - Rosenzweig, Ivana

AU - Rostampour, Masoumeh

AU - Saberi, Amin

AU - Schiel, Julian

AU - Schmidt, Christina

AU - Schrantee, Anouk

AU - Sciberras, Emma

AU - Silk, Tim J.

AU - Sim, Kang

AU - Smevik, Hanne

AU - Soares, Jair C.

AU - Spiegelhalder, Kai

AU - Stein, Dan J.

AU - Talwar, Puneet

AU - Tamm, Sandra

AU - Teresi, Giana l.

AU - Valk, Sofie L.

AU - Van Someren, Eus

AU - Vandewalle, Gilles

AU - Van Egroo, Maxime

AU - Völzke, Henry

AU - Walter, Martin

AU - Wassing, Rick

AU - Weber, Frederik D.

AU - Weihs, Antoine

AU - Westlye, Lars Tjelta

AU - Wright, Margaret J.

AU - Wu, Mon-Ju

AU - Zak, Nathalia

AU - Zarei, Mojtaba

PY - 2021/12

Y1 - 2021/12

N2 - Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine.

AB - Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine.

KW - ENIGMA consortium

KW - large-scale collaboration

KW - neurogenetics

KW - neuroimaging

KW - sleep

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U2 - 10.1111/jsr.13347

DO - 10.1111/jsr.13347

M3 - Review article

C2 - 33913199

SN - 1365-2869

VL - 30

SP - 1

EP - 20

JO - Journal of Sleep Research

JF - Journal of Sleep Research

IS - 6

M1 - e13347

ER -

ENIGMA-Sleep: challenges, opportunities, and the road map

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Keywords

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