Abstract
Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.
| Language | English |
|---|---|
| Pages | 3049-3058 |
| Number of pages | 10 |
| Journal | Quality of Life Research |
| Volume | 26 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 1 Nov 2017 |
| Externally published | Yes |
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Keywords
- Chinese
- EQ-5D
- Health state utility
- Quality of life
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Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China. / Si, Lei; Shi, Lei; Chen, Mingsheng; Palmer, Andrew J.
In: Quality of Life Research, Vol. 26, No. 11, 01.11.2017, p. 3049-3058.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China
AU - Si, Lei
AU - Shi, Lei
AU - Chen, Mingsheng
AU - Palmer, Andrew J.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.
AB - Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.
KW - Chinese
KW - EQ-5D
KW - Health state utility
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=85020297437&partnerID=8YFLogxK
U2 - 10.1007/s11136-017-1614-5
DO - 10.1007/s11136-017-1614-5
M3 - Article
VL - 26
SP - 3049
EP - 3058
JO - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
T2 - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
JF - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
SN - 0962-9343
IS - 11
ER -