Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China

Lei Si, Lei Shi, Mingsheng Chen, Andrew J. Palmer

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.

LanguageEnglish
Pages3049-3058
Number of pages10
JournalQuality of Life Research
Volume26
Issue number11
DOIs
Publication statusPublished - 1 Nov 2017
Externally publishedYes

Fingerprint

Benchmarking
China
Health
Population
Chronic Disease
Widowhood
Divorce

Keywords

  • Chinese
  • EQ-5D
  • Health state utility
  • Quality of life

Cite this

@article{7fbf653286274c3f952bfd9b17288835,
title = "Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China",
abstract = "Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.",
keywords = "Chinese, EQ-5D, Health state utility, Quality of life",
author = "Lei Si and Lei Shi and Mingsheng Chen and Palmer, {Andrew J.}",
year = "2017",
month = "11",
day = "1",
doi = "10.1007/s11136-017-1614-5",
language = "English",
volume = "26",
pages = "3049--3058",
journal = "Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation",
issn = "0962-9343",
publisher = "Springer, Springer Nature",
number = "11",

}

Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China. / Si, Lei; Shi, Lei; Chen, Mingsheng; Palmer, Andrew J.

In: Quality of Life Research, Vol. 26, No. 11, 01.11.2017, p. 3049-3058.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China

AU - Si, Lei

AU - Shi, Lei

AU - Chen, Mingsheng

AU - Palmer, Andrew J.

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.

AB - Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population. Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value <0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074. Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092–0.104) lower than those without chronic disease. Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.

KW - Chinese

KW - EQ-5D

KW - Health state utility

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=85020297437&partnerID=8YFLogxK

U2 - 10.1007/s11136-017-1614-5

DO - 10.1007/s11136-017-1614-5

M3 - Article

VL - 26

SP - 3049

EP - 3058

JO - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

T2 - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

JF - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

SN - 0962-9343

IS - 11

ER -