TY - JOUR
T1 - Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors
AU - Herbert, Annie
AU - Cruickshank, John Kennedy
AU - Laurent, Stéphane
AU - Boutouyrie, Pierre
AU - The Reference Values for Arterial Measurements Collaboration
AU - Shimada, Kazuyuki
AU - Kario, Kazuomi
AU - Miyashita, Hiroshi
AU - Eguchi, Kazuo
AU - Kohara, Katsuhiko
AU - Tabara, Yasuharu
AU - Imai, Yutaka
AU - Ito, Sadayoshi
AU - Hashimoto, Junichiro
AU - Uchiba, Kiyoshi
AU - Suzuki, Hiromichi
AU - Takenaka, Tsuneo
AU - Takazawa, Kenji
AU - Kino, Mineko
AU - Yamashina, Akira
AU - Tomiyama, Hirofumi
AU - Dohi, Yasuaki
AU - Takase, Hiroyuki
AU - Jouven, Xavier
AU - Empana, Jean Phillipe
AU - Pannier, Bruno
AU - Thomas, Frédérique
AU - Prescott, Eva
AU - Janner, Julie
AU - McEniery, Carmel
AU - Cockcroft, John
AU - Wilkinson, Ian
AU - Roman, Mary J.
AU - Devereux, Richard B.
AU - Teal, Valerie
AU - Townsend, Raymond
AU - Vermeersch, Sebastian
AU - Rietzschel, Ernst R.
AU - Van Bortel, Luc
AU - De Buyzere, Marc L.
AU - Segers, Patrick
AU - Gillebert, Thierry C.
AU - Wang, Ji Guang
AU - Li, Yan
AU - Lazar, Jason
AU - Salciccioli, Louis
AU - Cunha, Pedro
AU - Oliveira, Pedro
AU - Cotter, Jorge
AU - Vila, Isabel
AU - Sousa, Nuno
AU - Chirinos, Julio
AU - Medina-Lezama, Josefina
AU - Weber, Thomas
AU - Rammer, Martin
AU - O'Rourke, Michael F.
AU - Bernd, Eber
AU - Lassnig, Elisabeth
AU - Porodko, Michael
AU - Ammer, Marcus
AU - Wassertheurer, Siegfried
AU - Adji, Audrey
AU - Rosenkranz, Stefan
AU - Punzengruber, Christian
AU - Kvas, Erich
AU - Dufouil, Carole
AU - Tzourio, Christophe
AU - Nijpels, Giel
AU - Dekker, Jacqueline M.
AU - Stehouwer, Coen D.A.
AU - Ferreira, Isabel
AU - Twisk, Jos W.
AU - Smulders, Yvo M.
AU - Van De Laar, Roel J.
AU - Van Kallen, Carla J.
AU - Van Greevenbroek, Marleen M.
AU - Schalkwijk, Casper G.
AU - Vlachopoulos, Charalambos
AU - Aznaouridis, Constantinos
AU - Terentes-Printzios, Dimitrios
AU - Xaplanteris, Panos
AU - Stefanadis, Christodoulos
AU - Schutte, Aletta E.
AU - Fourie, Carla M.T.
AU - Van Rooyen, Johannes M.
AU - Mahmud, Azra
AU - Feely, John
AU - Ghiadoni, Lorenzo
AU - Stea, Francesco
AU - Bruno, Rosa Maria
AU - Cartoni, Giulia
AU - Armenia, Sabina
AU - Taddei, Stefano
AU - Seidlerova, Jitka
AU - Vanek, Jifi
AU - Filipovsky, Jan
AU - Mayer, Otto
AU - Lind, Lars
AU - Soveri, Inga
AU - Fellström, Bengt
AU - Zilmer, Mihkel
AU - Cavallini, Maria Chiara
AU - Pini, Riccardo
AU - Di Bari, Mauro
AU - Marchionni, Niccolo
AU - Masotti, Guilo
AU - Schillaci, Giuseppe
AU - Pucci, Giacomo
AU - Battista, Francesca
AU - Settimi, Laura
AU - Crilly, Michael A.
AU - Kumar, Vinod
AU - Clark, Hazel J.
AU - Scott, Neil W.
AU - Macdonald, Alan G.
AU - Williams, David J.
AU - Hillis, Graham S.
AU - Lee, Amanda J.
AU - De Vries, Alison
AU - Small, Gary R.
AU - Zanchetti, Alberto
AU - Bilo, Gregorz
AU - Taurino, Chiara
AU - McClure, John D.
AU - Schneider, Markus P.
AU - Kawecka-Jaszcz, Kalina
AU - Stolarz-Skrzypek, Katarzyna
AU - Klima, Łukasz
AU - Staessen, Jan A.
AU - Kuznetsova, Tatiana
AU - Redon, Josep
AU - Martinez, Fernando
AU - Rosei, Enrico Agabiti
AU - Melander, Olle
AU - Zannad, Faiez
AU - Rossignol, Patrick
AU - Collin, Cédric
AU - Lonati, Laura
AU - Dominiczak, Anna F.
AU - O'Rourke, Michael
AU - Petrak, Ondrej
AU - Štrauch, Branislav
AU - Rosa, Jan
AU - Widimský, Jirí
AU - Pipingas, Andrew
AU - Pase, Matthew P.
AU - Grima, Natalie A.
AU - Stough, Con
AU - Harris, Elizabeth
AU - Sellick, Laura
AU - Macpherson, Helen
AU - Pascualab, José Maria
AU - Rodilla, Enrique
AU - Costa, José Antonio
AU - Simon, Tabasomme
AU - Delles, Christian
AU - Dymott, Jane A.
AU - Neisius, Ulf
AU - Carty, David M.
AU - Fesler, Pierre
AU - Muiesan, Maria Lorenza
AU - Salvettia, Massimo
AU - Paini, Anna
AU - Tisler, Andras
AU - Zofi,
AU - Nemeth, Klara
AU - Marton, Adrienn
AU - El Haj Othmane, Taha
AU - Cseprekal, Orsolya
AU - Studinger, Peter
AU - Ibrahim, Nik Nor Izah Nik
AU - Rasool, Aida Hanum Ghulam
AU - Rahman, Abdul Rashid Abdul
AU - Wong, Abdul Rahim
AU - Protogerou, Athanasios D.
AU - Papaioannou, Theodore G.
AU - Sfikakis, Petros P.
AU - Fu, Yangweng
AU - Hu, Jihong
AU - Zhao, Liancheng
AU - Li, Nicole
AU - Jiang, Xiongjing
AU - Ok, Ercan
AU - Demirci, Meltem Sezis
AU - Gungor, Ozkan
AU - Orlova, I. A.
AU - Blankova, Z. N.
AU - Seredenina, E. M.
AU - Ageev, F. T.
AU - Orlova, I. A.
AU - Barinova, I. V.
AU - Seredenina, E. M.
AU - Ageev, F. T.
AU - Bellien, J.
AU - Iacob, M.
AU - Thuillez, C.
AU - Joannides,
AU - Erglis, Andrejs
AU - Mintale, Iveta
AU - Latkovskis, Gustavs
AU - Berzina, Marina
AU - Zabunova, Milana
AU - Krallisa, Agnese
AU - Smulyan, Harold
AU - Safar, Michel
AU - Zhadan, Andriy
AU - Tselukyo, Vira
AU - Bregvadze, Tiko
AU - Aydin, Ali
AU - Von Kodolitsch, Yskert
PY - 2014/11/21
Y1 - 2014/11/21
N2 - Aims: Estimated central systolic blood pressure (cSBP) and amplification (Brachial SBP-cSBP) are non-invasive measures potentially prognostic of cardiovascular (CV) disease. No worldwide, multiple-device reference values are available. We aimed to establish reference values for a worldwide general population standardizing between the different available methods of measurement. How these values were significantly altered by cardiovascular risk factors (CVRFs) was then investigated. Methods and results: Existing data from population surveys and clinical trials were combined, whether published or not. Reference values of cSBP and amplification were calculatedas percentiles for 'Normal' (no CVRFs) and 'Reference' (any CVRFs) populations. We included 45 436 subjects out of 82 930 that were gathered from 77 studies of 53 centres. Included subjects were apparently healthy, not treated for hypertension or dyslipidaemia, and free from overt CV disease and diabetes. Values of cSBP and amplification were stratified by brachial blood pressure categories and age decade in turn, both being stratifiedbysex. Amplification decreased with age and more so in males than in females. Sex was the most powerful factor associated with amplification with 6.6 mmHg (5.8-7.4) higher amplification in males than in females. Amplification was marginally but significantly influenced by CVRFs, with smoking and dyslipidaemia decreasing amplification, but increased with increasing levels of blood glucose. Conclusion: Typical values of cSBP and amplification in a healthy population and a population free of traditional CVRFs are now available according to age, sex, and brachial BP, providing values included from different devices with a wide geographical representation. Amplification is significantly influenced by CVRFs, but differently in men and women.
AB - Aims: Estimated central systolic blood pressure (cSBP) and amplification (Brachial SBP-cSBP) are non-invasive measures potentially prognostic of cardiovascular (CV) disease. No worldwide, multiple-device reference values are available. We aimed to establish reference values for a worldwide general population standardizing between the different available methods of measurement. How these values were significantly altered by cardiovascular risk factors (CVRFs) was then investigated. Methods and results: Existing data from population surveys and clinical trials were combined, whether published or not. Reference values of cSBP and amplification were calculatedas percentiles for 'Normal' (no CVRFs) and 'Reference' (any CVRFs) populations. We included 45 436 subjects out of 82 930 that were gathered from 77 studies of 53 centres. Included subjects were apparently healthy, not treated for hypertension or dyslipidaemia, and free from overt CV disease and diabetes. Values of cSBP and amplification were stratified by brachial blood pressure categories and age decade in turn, both being stratifiedbysex. Amplification decreased with age and more so in males than in females. Sex was the most powerful factor associated with amplification with 6.6 mmHg (5.8-7.4) higher amplification in males than in females. Amplification was marginally but significantly influenced by CVRFs, with smoking and dyslipidaemia decreasing amplification, but increased with increasing levels of blood glucose. Conclusion: Typical values of cSBP and amplification in a healthy population and a population free of traditional CVRFs are now available according to age, sex, and brachial BP, providing values included from different devices with a wide geographical representation. Amplification is significantly influenced by CVRFs, but differently in men and women.
KW - Adult
KW - Aged
KW - Aorta
KW - Arteries
KW - Arteriosclerosis
KW - Blood pressure
KW - Central pressure
KW - Humans
KW - Pulse
UR - http://www.scopus.com/inward/record.url?scp=84913589999&partnerID=8YFLogxK
U2 - 10.1093/eurheartj/ehu293
DO - 10.1093/eurheartj/ehu293
M3 - Article
C2 - 25112663
AN - SCOPUS:84913589999
SN - 0195-668X
VL - 35
SP - 3122
EP - 3133
JO - European Heart Journal
JF - European Heart Journal
IS - 44
ER -