Estimation of aortic pulse pressure using fourier velocity encoded M-mode MR

Valentina Taviani*, Stacey S. Hickson, Christopher J. Hardy, Andrew J. Patterson, Victoria E. Young, Carmel M. McEniery, Ian B. Wilkinson, Jonathan H. Gillard, Martin J. Graves

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Purpose To use a simplified hemodynamic model and Fourier-encoded velocity data to measure pulse pressure (PP) in the descending aorta. Materials and Methods A one-dimensional, cylindrically localized pulse sequence with Fourier velocity encoding (FVE) was used to obtain time-dependent velocity distributions along the descending aorta. Numerical evaluation of a simplified hemodynamic model, based on a cross-sectionally averaged form of the mass conservation equation, allowed estimation of the average pressure waveform and PP along 6-cm-long segments located within the descending aorta. Magnetic resonance (MR)-derived pressures were compared against applanation tonometry (AT) performed in healthy subjects (n = 18) and intravascular pressure measurements (IVPM) obtained in patients (n = 4) undergoing diagnostic cardiac angiography and then found to be either normal or with clinically insignificant coronary artery disease. Results The root mean square (RMS) error between MR- and AP-derived pressure waveforms was 11.7 ± 5.8%. With respect to IVPM, the RMS error ranged from 4.2% to 14.7%. In terms of pulse pressures, there was good agreement with both AT (bias = 0.99 mmHg; 95% limits of agreement (LOA) = [-5.0 to 7.0 mmHg]; range = 12.0 mmHg) and IVPM (bias = -1.82 mmHg; 95% LOA = [-7.2 to 3.5 mmHg]; range = 10.7 mmHg). Conclusion FVE M-mode and numerical evaluation of a simplified flow model can be used to estimate central pulse pressures noninvasively and accurately with respect to well-established gold standards. J. Magn. Reson. Imaging 2014;39:85-93. © 2013 Wiley Periodicals, Inc.

Original languageEnglish
Pages (from-to)85-93
Number of pages9
JournalJournal of Magnetic Resonance Imaging
Volume39
Issue number1
DOIs
Publication statusPublished - Jan 2014
Externally publishedYes

Keywords

  • aortic pulse pressure
  • cylindrical excitation
  • distensibility
  • Fourier velocity encoding

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