Estimation of central aortic pressure waveform features derived from the brachial cuff volume displacement waveform

Mark Butlin*, Ahmad Qasem, Alberto P. Avolio

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

    47 Citations (Scopus)

    Abstract

    There is increasing interest in non-invasive estimation of central aortic waveform parameters in the clinical setting. However, controversy has arisen around radial tonometric based systems due to the requirement of a trained operator or lack of ease of use, especially in the clinical environment. A recently developed device utilizes a novel algorithm for brachial cuff based assessment of aortic pressure values and waveform (SphygmoCor XCEL, AtCor Medical). The cuff was inflated to 10 mmHg below an individual's diastolic blood pressure and the brachial volume displacement waveform recorded. The aortic waveform was derived using proprietary digital signal processing and transfer function applied to the recorded waveform. The aortic waveform was also estimated using a validated technique (radial tonometry based assessment, SphygmoCor, AtCor Medical). Measurements were taken in triplicate with each device in 30 people (17 female) aged 22 to 79 years of age. An average for each device for each individual was calculated, and the results from the two devices were compared using regression and Bland-Altman analysis. A high correlation was found between the devices for measures of aortic systolic (R2=0.99) and diastolic (R2=0.98) pressure. Augmentation index and subendocardial viability ratio both had a between device R2 value of 0.82. The difference between devices for measured aortic systolic pressure was 0.5±1.8 mmHg, and for augmentation index, 1.8±7.0%. The brachial cuff based approach, with an individualized sub-diastolic cuff pressure, provides an operator independent method of assessing not only systolic pressure, but also aortic waveform features, comparable to existing validated tonometric-based methods.

    Original languageEnglish
    Title of host publication2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
    EditorsNigel Lovell
    Place of PublicationPiscataway, N.J.
    PublisherInstitute of Electrical and Electronics Engineers (IEEE)
    Pages2591-2594
    Number of pages4
    Volume2012
    ISBN (Electronic)9781457717871, 9781424441204
    ISBN (Print)9781424441198
    DOIs
    Publication statusPublished - Sep 2012
    Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
    Duration: 28 Aug 20121 Sep 2012

    Publication series

    NameProceedings of the annual international conference of the IEEE Engineering in Medicine and Biology Society
    PublisherIEEE
    ISSN (Print)1094-687X
    ISSN (Electronic)1558-4615

    Other

    Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
    CountryUnited States
    CitySan Diego, CA
    Period28/08/121/09/12

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