EUROCarbDB: An open-access platform for glycoinformatics

Claus Wilhelm Von Der Lieth, Ana Ardá Freire, Dennis Blank, Matthew P. Campbell, Alessio Ceroni, David R. Damerell, Anne Dell, Raymond A. Dwek, Beat Ernst, Rasmus Fogh, Martin Frank, Hildegard Geyer, Rudolf Geyer, Mathew J. Harrison, Kim Henrick, Stefan Herget, William E. Hull, John Ionides, Hiren J. Joshi, Johannis P. KamerlingBas R. Leeflang, Thomas Lütteke, Magnus Lundborg, Kai Maass, Anthony Merry, René Ranzinger, Jimmy Rosen, Louise Royle, Pauline M. Rudd, Siegfried Schloissnig, Roland Stenutz, Wim F. Vranken, Göran Widmalm, Stuart M. Haslam

    Research output: Contribution to journalArticlepeer-review

    103 Citations (Scopus)

    Abstract

    The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing glycan structures, their biological context and, when available, primary and interpreted analytical data from high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance experiments. Database content can be accessed via a web-based user interface. The database is complemented by a suite of glycoinformatics tools, specifically designed to assist the elucidation and submission of glycan structure and experimental data when used in conjunction with contemporary carbohydrate research workflows. All software tools and source code are licensed under the terms of the Lesser General Public License, and publicly contributed structures and data are freely accessible. The public test version of the web interface to the EUROCarbDB can be found at http://www.ebi.ac.uk/eurocarb.

    Original languageEnglish
    Pages (from-to)493-502
    Number of pages10
    JournalGlycobiology
    Volume21
    Issue number4
    DOIs
    Publication statusPublished - Apr 2011

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