TY - JOUR
T1 - Evaluating animal models
T2 - Some taxonomic worries
AU - Degeling, Chris
AU - Johnson, Jane
PY - 2013/4
Y1 - 2013/4
N2 - The seminal 1993 article by LaFollette and Shanks "Animal Models in Biomedical Research: Some Epistemological Worries" introduced an influential taxonomy into the debate about the value of animal experimentation. The distinction they made between hypothetical and causal analog models served to highlight a concern regarding extrapolating results obtained in animal models to human subjects, which endures today. Although their taxonomy has made a significant contribution to the field, we maintain that it is flawed, and instead, we offer a new practice-oriented taxonomy of animal models as a means to allow philosophers, modelers, and other interested parties to discuss the epistemic merits and shortcomings, purpose, and predictive capacities of specific modeling practices.
AB - The seminal 1993 article by LaFollette and Shanks "Animal Models in Biomedical Research: Some Epistemological Worries" introduced an influential taxonomy into the debate about the value of animal experimentation. The distinction they made between hypothetical and causal analog models served to highlight a concern regarding extrapolating results obtained in animal models to human subjects, which endures today. Although their taxonomy has made a significant contribution to the field, we maintain that it is flawed, and instead, we offer a new practice-oriented taxonomy of animal models as a means to allow philosophers, modelers, and other interested parties to discuss the epistemic merits and shortcomings, purpose, and predictive capacities of specific modeling practices.
UR - http://www.scopus.com/inward/record.url?scp=84875198318&partnerID=8YFLogxK
U2 - 10.1093/jmp/jht004
DO - 10.1093/jmp/jht004
M3 - Article
C2 - 23444231
AN - SCOPUS:84875198318
SN - 0360-5310
VL - 38
SP - 91
EP - 106
JO - Journal of Medicine and Philosophy (United Kingdom)
JF - Journal of Medicine and Philosophy (United Kingdom)
IS - 2
ER -