Evaluation of a low-dose/slow-rotating SPECT-CT system

M. Hamann*, M. Aldridge, J. Dickson, R. Endozo, K. Lozhkin, B. F. Hutton

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    35 Citations (Scopus)


    The 4-slice CT that forms part of the GE Infinia Hawkeye-4 SPECT-CT scanner (Hawkeye) is evaluated against the diagnostic 16-slice CT that is incorporated in the GE Discovery ST PET-CT system (DST). The x-ray tube of the slow-rotating Hawkeye system (23 s/rotation) operates at approximately a third of the dose of diagnostic systems as used for conventional diagnostic imaging. Image reconstruction is optimized for low noise. High-contrast spatial resolution significantly falls behind diagnostic figures: the average of MTF50 and MTF10 (resolution where the MTF has fallen to 50% and 10%) is 2.8 ± 0.1 cm-1 for Hawkeye and 5.3 ± 0.1 cm-1 for the DST (standard reconstruction filters). Resolution in the direction of the couch movement (z coordinate) is governed by the fixed Hawkeye slice width of 5 mm. Reconstruction accuracy is found to be increased by reducing the default z increment from 4.4 mm to 2.2 mm. Low-contrast object detectability is superior compared with diagnostic systems operating in the Hawkeye dose range. In the diagnostic dose regime, however, small low-contrast details remain visible in DST that are not detectable with Hawkeye. Although not of diagnostic quality, the low-dose Hawkeye provides appropriate data for SPECT attenuation correction and anatomical localization capability.

    Original languageEnglish
    Pages (from-to)2495-2508
    Number of pages14
    JournalPhysics in Medicine and Biology
    Issue number10
    Publication statusPublished - 21 May 2008


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