Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients

Edgardo A. Crisostomo*, Pamela W. Duncan, Martha Propst, Deborah V. Dawson, James N. Davis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

295 Citations (Scopus)

Abstract

We conducted a double‐blind pilot study of 8 patients with established cerebral infarction to evaluate the effect of a single dose of amphetamine on recovery of motor function using the Fugl‐Meyer scale. Four patients received amphetamine; the rest were given placebo. All underwent a session of physical therapy. Patients treated with amphetamine obtained greater increments in motor scores than the controls. Along with animal studies, these findings may allow the development of a pharmacological approach to stroke rehabilitation.

Original languageEnglish
Pages (from-to)94-97
Number of pages4
JournalAnnals of Neurology
Volume23
Issue number1
DOIs
Publication statusPublished - 1988
Externally publishedYes

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