@inbook{cdad79de76ff46fdaa1192c027fe56c3,
title = "Examining cellular responses to kinase drug inhibition through phosphoproteome mapping of substrates",
abstract = "This chapter provides a detailed description for mass spectrometry-based phosphoproteomics analysis. We describe sample preparation, phosphopeptide enrichment, mass spectrometry acquisition, label-free data analysis and statistical analysis. This technique can be employed to characterize cell signaling networks, and is particularly useful to monitor cellular responses to kinase drug inhibitors.",
keywords = "Phosphoproteomics, Phosphopeptide enrichment, Mass spectrometry, Label-free",
author = "Daniel Bucio-Noble and Crystal Semaan and Molloy, {Mark P.}",
year = "2019",
doi = "10.1007/978-1-4939-8891-4_8",
language = "English",
isbn = "9781493988907",
series = "Methods in Molecular Biology",
publisher = "Humana Press",
pages = "141--152",
editor = "Slava Ziegler and Herbert Waldmann",
booktitle = "Systems chemical biology",
address = "United States",
}