Examining patient activation and other factors associated with changes in pain and function following best evidence osteoarthritis care

Jillian Peta Eyles; Kathryn Mills; Barbara R. Lucas; Sarah R. Robbins; Rachel L. O'Connell; Matthew Williams; Hans Lee; Scott Appleton; David J. Hunter

doi:10.1016/j.ocarto.2021.100197

Examining patient activation and other factors associated with changes in pain and function following best evidence osteoarthritis care

Jillian Peta Eyles^*, Kathryn Mills, Barbara R. Lucas, Sarah R. Robbins, Rachel L. O'Connell, Matthew Williams, Hans Lee, Scott Appleton, David J. Hunter

^*Corresponding author for this work

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Abstract

Objectives: The primary objective was to examine baseline patient activation as a prognostic factor for changes in pain and function following participation in an osteoarthritis management program. The secondary objective was to examine other prognostic factors from existing literature (e.g. employment, functional performance, depression, comorbidities). Method: One-hundred-and-eleven participants with knee osteoarthritis were assessed at 0-, 12- and 26-weeks in this prospective clinical cohort. Demographic variables, timed-up-and-go (TUG), patient activation measure (PAM-13), Depression Anxiety Stress Scale and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were collected. Multivariable linear regression examined relationships between prognostic factors and pain and function at 12- and 26-weeks. Results: Complete 12- and 26-week data were available for 89 and 74 participants respectively, 66 % female, 66.8 (SD 10.0) years, 74 % unemployed, 66 % finished high school or higher, 12 % on joint arthroplasty waitlists. Baseline PAM-13 scores were not associated with changes in pain or function at 12- or 26-weeks. Employment status (β = 9.17 (95 % CI 2.11, 16.24), p = 0.01) and TUG (β = −1.20 (95 % CI -1.91, −0.49), p < 0.01) were associated with changes in pain at week-12. Employment status (β = 11.60 (95 % CI 5.31, 17.90), p < 0.01) and TUG (β = −1.10 (95%CI -1.78, −0.43), p < 0.01) were associated with 12-week function. Baseline TUG (β = −1.32 (95 % CI -2.40, −0.23), p = 0.02) was associated with week-26 WOMAC function. Conclusions: Baseline PAM-13 scores were not associated with changes in pain and function at any timepoint. Employment status and TUG were associated with changes in pain and function at 12-weeks, TUG was associated with 26-week function.

Original language	English
Article number	100197
Pages (from-to)	1-8
Number of pages	8
Journal	Osteoarthritis and Cartilage Open
Volume	3
Issue number	3
DOIs	https://doi.org/10.1016/j.ocarto.2021.100197
Publication status	Published - Sept 2021
Externally published	Yes

Bibliographical note

Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Knee
Multidisciplinary intervention
Osteoarthritis
Outcome assessment
Patient activation
Rehabilitation

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Publisher version (open access)Final published version, 601 KBLicence: CC BY-NC-ND

Cite this

Eyles, J. P., Mills, K., Lucas, B. R., Robbins, S. R., O'Connell, R. L., Williams, M., Lee, H., Appleton, S., & Hunter, D. J. (2021). Examining patient activation and other factors associated with changes in pain and function following best evidence osteoarthritis care. Osteoarthritis and Cartilage Open, 3(3), 1-8. Article 100197. https://doi.org/10.1016/j.ocarto.2021.100197

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title = "Examining patient activation and other factors associated with changes in pain and function following best evidence osteoarthritis care",

abstract = "Objectives: The primary objective was to examine baseline patient activation as a prognostic factor for changes in pain and function following participation in an osteoarthritis management program. The secondary objective was to examine other prognostic factors from existing literature (e.g. employment, functional performance, depression, comorbidities). Method: One-hundred-and-eleven participants with knee osteoarthritis were assessed at 0-, 12- and 26-weeks in this prospective clinical cohort. Demographic variables, timed-up-and-go (TUG), patient activation measure (PAM-13), Depression Anxiety Stress Scale and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were collected. Multivariable linear regression examined relationships between prognostic factors and pain and function at 12- and 26-weeks. Results: Complete 12- and 26-week data were available for 89 and 74 participants respectively, 66 % female, 66.8 (SD 10.0) years, 74 % unemployed, 66 % finished high school or higher, 12 % on joint arthroplasty waitlists. Baseline PAM-13 scores were not associated with changes in pain or function at 12- or 26-weeks. Employment status (β = 9.17 (95 % CI 2.11, 16.24), p = 0.01) and TUG (β = −1.20 (95 % CI -1.91, −0.49), p < 0.01) were associated with changes in pain at week-12. Employment status (β = 11.60 (95 % CI 5.31, 17.90), p < 0.01) and TUG (β = −1.10 (95%CI -1.78, −0.43), p < 0.01) were associated with 12-week function. Baseline TUG (β = −1.32 (95 % CI -2.40, −0.23), p = 0.02) was associated with week-26 WOMAC function. Conclusions: Baseline PAM-13 scores were not associated with changes in pain and function at any timepoint. Employment status and TUG were associated with changes in pain and function at 12-weeks, TUG was associated with 26-week function.",

keywords = "Knee, Multidisciplinary intervention, Osteoarthritis, Outcome assessment, Patient activation, Rehabilitation",

author = "Eyles, {Jillian Peta} and Kathryn Mills and Lucas, {Barbara R.} and Robbins, {Sarah R.} and O'Connell, {Rachel L.} and Matthew Williams and Hans Lee and Scott Appleton and Hunter, {David J.}",

note = "Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.",

year = "2021",

month = sep,

doi = "10.1016/j.ocarto.2021.100197",

language = "English",

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T1 - Examining patient activation and other factors associated with changes in pain and function following best evidence osteoarthritis care

AU - Eyles, Jillian Peta

AU - Mills, Kathryn

AU - Lucas, Barbara R.

AU - Robbins, Sarah R.

AU - O'Connell, Rachel L.

AU - Williams, Matthew

AU - Lee, Hans

AU - Appleton, Scott

AU - Hunter, David J.

N1 - Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

PY - 2021/9

Y1 - 2021/9

N2 - Objectives: The primary objective was to examine baseline patient activation as a prognostic factor for changes in pain and function following participation in an osteoarthritis management program. The secondary objective was to examine other prognostic factors from existing literature (e.g. employment, functional performance, depression, comorbidities). Method: One-hundred-and-eleven participants with knee osteoarthritis were assessed at 0-, 12- and 26-weeks in this prospective clinical cohort. Demographic variables, timed-up-and-go (TUG), patient activation measure (PAM-13), Depression Anxiety Stress Scale and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were collected. Multivariable linear regression examined relationships between prognostic factors and pain and function at 12- and 26-weeks. Results: Complete 12- and 26-week data were available for 89 and 74 participants respectively, 66 % female, 66.8 (SD 10.0) years, 74 % unemployed, 66 % finished high school or higher, 12 % on joint arthroplasty waitlists. Baseline PAM-13 scores were not associated with changes in pain or function at 12- or 26-weeks. Employment status (β = 9.17 (95 % CI 2.11, 16.24), p = 0.01) and TUG (β = −1.20 (95 % CI -1.91, −0.49), p < 0.01) were associated with changes in pain at week-12. Employment status (β = 11.60 (95 % CI 5.31, 17.90), p < 0.01) and TUG (β = −1.10 (95%CI -1.78, −0.43), p < 0.01) were associated with 12-week function. Baseline TUG (β = −1.32 (95 % CI -2.40, −0.23), p = 0.02) was associated with week-26 WOMAC function. Conclusions: Baseline PAM-13 scores were not associated with changes in pain and function at any timepoint. Employment status and TUG were associated with changes in pain and function at 12-weeks, TUG was associated with 26-week function.

AB - Objectives: The primary objective was to examine baseline patient activation as a prognostic factor for changes in pain and function following participation in an osteoarthritis management program. The secondary objective was to examine other prognostic factors from existing literature (e.g. employment, functional performance, depression, comorbidities). Method: One-hundred-and-eleven participants with knee osteoarthritis were assessed at 0-, 12- and 26-weeks in this prospective clinical cohort. Demographic variables, timed-up-and-go (TUG), patient activation measure (PAM-13), Depression Anxiety Stress Scale and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were collected. Multivariable linear regression examined relationships between prognostic factors and pain and function at 12- and 26-weeks. Results: Complete 12- and 26-week data were available for 89 and 74 participants respectively, 66 % female, 66.8 (SD 10.0) years, 74 % unemployed, 66 % finished high school or higher, 12 % on joint arthroplasty waitlists. Baseline PAM-13 scores were not associated with changes in pain or function at 12- or 26-weeks. Employment status (β = 9.17 (95 % CI 2.11, 16.24), p = 0.01) and TUG (β = −1.20 (95 % CI -1.91, −0.49), p < 0.01) were associated with changes in pain at week-12. Employment status (β = 11.60 (95 % CI 5.31, 17.90), p < 0.01) and TUG (β = −1.10 (95%CI -1.78, −0.43), p < 0.01) were associated with 12-week function. Baseline TUG (β = −1.32 (95 % CI -2.40, −0.23), p = 0.02) was associated with week-26 WOMAC function. Conclusions: Baseline PAM-13 scores were not associated with changes in pain and function at any timepoint. Employment status and TUG were associated with changes in pain and function at 12-weeks, TUG was associated with 26-week function.

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KW - Multidisciplinary intervention

KW - Osteoarthritis

KW - Outcome assessment

KW - Patient activation

KW - Rehabilitation

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Examining patient activation and other factors associated with changes in pain and function following best evidence osteoarthritis care

Abstract

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